急性淋巴细胞白血病诱导化疗期间由构巢曲霉感染引起的脑脓肿
Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia.
作者信息
Sadarangani Manish, Harvey Melissa, McDonald Allison, Speert David P, Dix David
机构信息
*Department of Paediatrics, Division of Infectious Diseases ‡Department of Paediatrics, Division of Hematology and Oncology, University of British Columbia and BC Children's Hospital §Child and Family Research Institute, Vancouver, BC, Canada †Department of Paediatrics, University of Oxford, Oxford, UK.
出版信息
J Pediatr Hematol Oncol. 2015 Aug;37(6):e384-6. doi: 10.1097/MPH.0000000000000351.
We present the case of a 3-year-old boy who was diagnosed with cerebral abscesses due to Aspergillus nidulans infection on day 28 of induction chemotherapy for acute lymphoblastic leukemia. He responded well to treatment with voriconazole and caspofungin, making a full recovery. There are very few cases of invasive aspergillosis reported in children during induction chemotherapy for acute leukemia and A. nidulans is rare in the absence of chronic granulomatous disease.
我们报告一例3岁男孩的病例，该男孩在急性淋巴细胞白血病诱导化疗第28天时被诊断为因构巢曲霉感染导致的脑脓肿。他对伏立康唑和卡泊芬净治疗反应良好，完全康复。在儿童急性白血病诱导化疗期间，侵袭性曲霉病的报道病例非常少，并且在没有慢性肉芽肿病的情况下，构巢曲霉很罕见。
Zotero 插件