部分蛋白质结构域：进化见解与生物信息学挑战
Partial protein domains: evolutionary insights and bioinformatics challenges.
作者信息
Kelley Lawrence A, Sternberg Michael J E
机构信息
Structural Bioinformatics Group, Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK.
出版信息
Genome Biol. 2015 May 19;16(1):100. doi: 10.1186/s13059-015-0663-8.
Abstract
Protein domains are generally thought to correspond to units of evolution. New research raises questions about how such domains are defined with bioinformatics tools and sheds light on how evolution has enabled partial domains to be viable.
摘要
蛋白质结构域通常被认为对应于进化单元。新的研究对如何使用生物信息学工具定义这些结构域提出了疑问，并揭示了进化如何使部分结构域能够存活。
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