Becq Aymeric, Ozenne Violaine, Plessier Aurélie, Valleur Patrice, Dray Xavier
Aymeric Becq, Violaine Ozenne, Xavier Dray, Department of Gastroenterology and Hepatology, Sorbonne Paris Cité Paris 7 University & APHP Lariboisière Hospital, 75010 Paris, France.
World J Gastroenterol. 2015 May 14;21(18):5749-50. doi: 10.3748/wjg.v21.i18.5749.
Gastric antral vascular ectasia (GAVE) may cause gastrointestinal bleeding (GIB). The treatment of GAVE relies on endoscopic approaches such as electrocoagulation (argon plasma coagulation, laser therapy, heater probe therapy, radiofrequency ablation), cryotherapy, and band ligation. In refractory cases, antrectomy may be considered. In the event of an associated cirrhosis and portal hypertension, it has been suggested that antrectomy could be an option, provided the mortality risk isn't considered too great. We report the case of a 67-year-old cirrhotic patient who presented with GAVE related GIB, unresponsive to multiple endoscopic treatments. The patient had a good liver function (model for end-stage disease 10). After a multidisciplinary meeting, a transjugular intrahepatic portosystemic shunt (TIPS) procedure was performed, in order to treat the cirrhosis associated ascites. The outcome was successful. An antrectomy was then performed, with no recurrence of GIB and no transfusion need during three months of follow up. In this case, the TIPS procedure achieved a complete ascites regression, allowing a safer surgical treatment of the GAVE-related GIB.
胃窦血管扩张症(GAVE)可能导致胃肠道出血(GIB)。GAVE的治疗依赖于内镜治疗方法,如电凝术(氩离子凝固术、激光治疗、热探头治疗、射频消融)、冷冻疗法和套扎术。对于难治性病例,可考虑进行胃窦切除术。如果伴有肝硬化和门静脉高压,有人认为只要死亡风险不是太大,胃窦切除术可能是一种选择。我们报告一例67岁的肝硬化患者,该患者因GAVE相关的GIB就诊,对多种内镜治疗均无反应。患者肝功能良好(终末期肝病模型评分为10分)。经过多学科会诊后,为治疗与肝硬化相关的腹水,实施了经颈静脉肝内门体分流术(TIPS),结果成功。随后进行了胃窦切除术,在三个月的随访期间,GIB未复发,也无需输血。在本病例中,TIPS手术使腹水完全消退,从而使GAVE相关GIB的手术治疗更安全。