Hilal Talal, Woods Ryan
Department of Internal Medicine , University of Kentucky , Lexington, KY , USA.
Oxf Med Case Reports. 2015 Feb 16;2015(2):191-3. doi: 10.1093/omcr/omv005. eCollection 2015 Feb.
Brugada syndrome is an important cause of sudden cardiac death and should be recognized in asymptomatic patients with characteristic electrocardiographic (ECG) findings. We report a case of a 59-year-old male who presented with fever and generalized malaise after a camping trip with confirmed tick exposure. Initial diagnostic work-up included an ECG, which showed incidental ST-segment elevation in the right precordial leads consistent with a type 1 ECG pattern seen in Brugada syndrome. He was diagnosed with fever-induced Brugada syndrome and treated with doxycycline and antipyretics. The type 1 ECG pattern resolved a few hours later with a resultant right bundle branch block. Implantable cardioverter-defibrillator implantation was not indicated after risk stratification. The case highlights the importance of considering Brugada syndrome in patients with characteristic ECG changes in the setting of fever, and reviews the latest criteria for diagnosis, management and risk stratification of this fatal condition.
Brugada综合征是心脏性猝死的重要原因,对于有特征性心电图(ECG)表现的无症状患者应予以识别。我们报告一例59岁男性病例,该患者在一次露营旅行后出现发热和全身不适,旅行中已确认有蜱虫叮咬史。初步诊断检查包括心电图,结果显示右胸前导联意外出现ST段抬高,与Brugada综合征所见的1型心电图模式一致。他被诊断为发热诱发的Brugada综合征,并接受了强力霉素和退烧药治疗。数小时后,1型心电图模式消失,继而出现右束支传导阻滞。风险分层后未建议植入植入式心脏复律除颤器。该病例强调了在发热情况下出现特征性心电图改变的患者中考虑Brugada综合征的重要性,并回顾了这种致命疾病的最新诊断、管理和风险分层标准。