Joyseeree Ranveer, Abou Sabha Rami, Mueller Henning
Eidgenössische Technische Hochschule (ETH), Zürich, Switzerland.
University of Applied Sciences Western Switzerland (HES-SO), Sierre, Switzerland.
Stud Health Technol Inform. 2015;210:850-4.
A machine-learning framework to identify the specific disease afflicting certain patients diagnosed with Neurological and Neuromuscular Diseases (NND) or Juvenile Idiopathic Arthritis (JIA) using only gait analysis data is presented. Classifying such data into disease types consumes valuable clinical time that may be better spent. Effective classification also facilitates its future retrieval. To prove the feasibility of the approach, we applied it to the simpler case of identifying the disease class of patients with a view to extending the method to specific diseases in future work. Standard clinical gait information of healthy individuals, and NND/JIA patients was sourced from hospitals participating in MD-PAEDIGREE. To classify the data into one of the three categories: healthy, NND, and JIA, certain parameters were carefully selected from the signals and used to train Random Forest (RF), boosting, Multilayer Perceptron (MLP), and Support Vector Machine (SVM) classifiers. Cross-validation was used to test the effectiveness of our approach and it yields a classification accuracy of 100% for RF, SVM, and MLP classifiers and 96.4% for boosting. Training and testing for all the classifiers took mere milliseconds, providing opportunities for real-time applications. To extend the method to the identification of specific illnesses, more discerning features from the gait data are currently being investigated. Moreover, a larger dataset is being gathered. Finally, we are attempting to reduce the number of features used for classification in order to further decrease computation time and algorithm complexity.
本文提出了一种机器学习框架,该框架仅使用步态分析数据来识别患有神经和神经肌肉疾病(NND)或青少年特发性关节炎(JIA)的特定患者所患的具体疾病。将此类数据分类为疾病类型会消耗宝贵的临床时间,而这些时间可能有更好的用途。有效的分类也便于其未来的检索。为了证明该方法的可行性,我们将其应用于识别患者疾病类别的更简单案例,以期在未来的工作中将该方法扩展到特定疾病。健康个体以及NND/JIA患者的标准临床步态信息来自参与MD - PAEDIGREE的医院。为了将数据分类为健康、NND和JIA这三类之一,我们从信号中仔细选择了某些参数,并用于训练随机森林(RF)、提升、多层感知器(MLP)和支持向量机(SVM)分类器。交叉验证用于测试我们方法的有效性,结果显示RF、SVM和MLP分类器的分类准确率为100%,提升分类器的准确率为96.4%。所有分类器的训练和测试仅需几毫秒,为实时应用提供了机会。为了将该方法扩展到特定疾病的识别,目前正在研究步态数据中更具辨别力的特征。此外,正在收集更大的数据集。最后,我们正在尝试减少用于分类的特征数量,以进一步减少计算时间和算法复杂度。