Avila Daniel D, D'Ávila Jeferson, Góis Carlos, Barretto Luíza
ENT Discipline, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
DME, Universidade Federal de Sergipe, Aracaju, SE, Brazil.
Int Arch Otorhinolaryngol. 2014 Oct;18(4):352-6. doi: 10.1055/s-0034-1376431. Epub 2014 Jul 22.
Introduction Premalignant lesions are considered both a hyperplastic and dysplastic stage of epithelial lesions in the glottic larynx that may or may not progress into an invasive carcinoma. The evolution of laryngoscopic procedures in outpatients has provided better access to important information for safe and easy diagnosis of laryngeal pathologies. Objective The goal of this study was to determine the accuracy of the preoperative exam for diagnosis of premalignant laryngeal lesions and their connection with benign diseases of the vocal folds, as well as to assess their epidemiologic characteristics. Methods This is a retrospective and longitudinal cohort study performed through the review of surgical records of patients who underwent laryngeal microsurgery performed by a single surgeon from 1990 to 2009. Results Preoperative assessment of outpatients was 64.4% accurate. Vocal fold cysts were the most frequently associated benign lesions. The patients who apparently had premalignant lesions represented 10.57% of those who underwent laryngeal microsurgery. Premalignant lesions prevailed in men (69.49%) age from 41 to 50 years (32.20%). Conclusion Although the evolution of laryngoscopic procedures in outpatients has provided better access to important information for safe and easy diagnosis of laryngeal pathologies, about one-third of premalignant lesions are diagnosed just during the laryngeal microsurgery. Cysts were the most prevalent concomitant benign lesion of the vocal folds. Males were more prevalent than females and the predominant age bracket was between 41 and 50 years.
癌前病变被认为是声门喉上皮病变的增生和发育异常阶段，可能会也可能不会发展为浸润性癌。门诊喉镜检查方法的发展为安全、轻松地诊断喉部疾病提供了更好的重要信息获取途径。目的：本研究的目的是确定术前检查对诊断喉癌前病变的准确性及其与声带良性疾病的关联，并评估其流行病学特征。方法：这是一项回顾性纵向队列研究，通过回顾1990年至2009年由一名外科医生进行喉显微手术的患者的手术记录来进行。结果：门诊患者的术前评估准确率为64.4%。声带囊肿是最常见的相关良性病变。明显患有癌前病变的患者占接受喉显微手术患者的10.57%。癌前病变在41至50岁的男性中占主导（69.49%，32.20%）。结论：尽管门诊喉镜检查方法的发展为安全、轻松地诊断喉部疾病提供了更好的重要信息获取途径，但仍有大约三分之一的癌前病变是在喉显微手术期间才被诊断出来。囊肿是声带最常见的伴随良性病变。男性比女性更常见，主要年龄范围在41至50岁之间。
