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术中神经反应遥测与神经恢复功能:成人与儿童的比较研究

Intraoperative Neural Response Telemetry and Neural Recovery Function: a Comparative Study between Adults and Children.

作者信息

Carvalho Bettina, Hamerschmidt Rogerio, Wiemes Gislaine

机构信息

ENT Department, Instituto Paranaense de Otorrinolaringologia - IPO, Curitiba, Brazil.

Department of Fonoaudiology, IPO, Curitiba, Brazil.

出版信息

Int Arch Otorhinolaryngol. 2015 Jan;19(1):10-5. doi: 10.1055/s-0034-1372509. Epub 2014 Apr 2.

DOI:10.1055/s-0034-1372509
PMID:25992145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4392512/
Abstract

Introduction Neural response telemetry (NRT) is a method of capturing the action potential of the distal portion of the auditory nerve in cochlear implant (CI) users, using the CI itself to elicit and record the answers. In addition, it can also measure the recovery function of the auditory nerve (REC), that is, the refractory properties of the nerve. It is not clear in the literature whether the responses from adults are the same as those from children. Objective To compare the results of NRT and REC between adults and children undergoing CI surgery. Methods Cross-sectional, descriptive, and retrospective study of the results of NRT and REC for patients undergoing IC at our service. The NRT is assessed by the level of amplitude (microvolts) and REC as a function of three parameters: A (saturation level, in microvolts), t0 (absolute refractory period, in seconds), and tau (curve of the model function), measured in three electrodes (apical, medial, and basal). Results Fifty-two patients were evaluated with intraoperative NRT (26 adults and 26 children), and 24 with REC (12 adults and 12 children). No statistically significant difference was found between intraoperative responses of adults and children for NRT or for REC's three parameters, except for parameter A of the basal electrode. Conclusion The results of intraoperative NRT and REC were not different between adults and children, except for parameter A of the basal electrode.

摘要

引言 神经反应遥测(NRT)是一种在人工耳蜗(CI)使用者中捕捉听神经远端动作电位的方法,利用CI本身来引发并记录反应。此外,它还能测量听神经的恢复功能(REC),即神经的不应期特性。文献中尚不清楚成人的反应是否与儿童相同。目的 比较接受CI手术的成人和儿童的NRT和REC结果。方法 对在我院接受CI手术患者的NRT和REC结果进行横断面、描述性和回顾性研究。NRT通过振幅水平(微伏)进行评估,REC则作为三个参数的函数进行评估:A(饱和水平,微伏)、t0(绝对不应期,秒)和tau(模型函数曲线),在三个电极(顶端、中间和基底)上进行测量。结果 52例患者接受了术中NRT评估(26例成人和26例儿童),24例接受了REC评估(12例成人和12例儿童)。除基底电极的参数A外,成人和儿童术中NRT或REC的三个参数的反应在统计学上无显著差异。结论 除基底电极的参数A外,成人和儿童术中NRT和REC的结果无差异。

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Cochlear implant: correlation of nerve function recovery, auditory deprivation and etiology.人工耳蜗:神经功能恢复、听觉剥夺与病因学的相关性
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