Emadi Maryam, Rezaei Mohammad, Najafi Sirvan, Faramarzi Ali, Farahani Farhad
1School of Rehabilitation Sciences, Hamadan University of Medical Sciences & Health Services, Hamadan, Iran.
2Hamadan University of Medical Sciences & Health Services, Hamadan, Iran.
Indian J Otolaryngol Head Neck Surg. 2018 Mar;70(1):115-118. doi: 10.1007/s12070-015-0824-9. Epub 2015 Jan 20.
The aim of this study was to investigate the possible role of cochlear outer hair cell function with TEOAE and DPOAE tests in patients with normal hearing and tinnitus. 25 tinnitus patients with normal hearing sensitivity selected as study group. Control group consist of 50 normal hearing subjects without tinnitus. All subjects had thresholds below 25 dBHL at frequencies 250-8,000 Hz, tympanogram type A and normal acoustic reflex thresholds. TEOAE were recorded with click stimulus at 80 dB SPL at 1,000, 2,000, 3,000 and 4000 Hz. DPOAE were measured at frequencies 1,000-8,000 Hz and intensity of L1 55 dB SPL and L2 65 dB SPL. Amplitude of DPOAE and TEOAE were decreased in all frequencies in study group. There was significant difference regarding prevalence abnormal TEOAE and DPOAE between study group and control group. There was relationship between dysfunction of outer hair cells and tinnitus in subjects with normal hearing.
本研究的目的是通过瞬态诱发性耳声发射（TEOAE）和畸变产物耳声发射（DPOAE）测试，探讨耳蜗外毛细胞功能在听力正常的耳鸣患者中可能发挥的作用。选取25例听力正常的耳鸣患者作为研究组。对照组由50例无耳鸣的听力正常受试者组成。所有受试者在250 - 8000Hz频率下的听阈均低于25dBHL，鼓室导抗图为A型，声反射阈正常。采用80dB SPL的短声刺激记录1000、2000、3000和4000Hz频率下的TEOAE。在1000 - 8000Hz频率下测量DPOAE，L1强度为55dB SPL，L2强度为65dB SPL。研究组所有频率下DPOAE和TEOAE的幅值均降低。研究组与对照组之间TEOAE和DPOAE异常发生率存在显著差异。听力正常的受试者中，外毛细胞功能障碍与耳鸣之间存在关联。
