Stocchero Guilherme Flosi
Instituto de Cirurgia Plástica Santa Cruz, São Paulo, SP, Brazil.
Einstein (Sao Paulo). 2015 Jan-Mar;13(1):103-5. doi: 10.1590/S1679-45082015RC2907. Epub 2015 Mar 3.
Storiform collagenoma is a rare tumor, which originates from the proliferation of fibroblasts that show increased production of type-I collagen. It is usually found in the face, neck and extremities, but it can also appear in the trunk, scalp and, less frequently, in the oral mucosa and the nail bed. It affects both sexes, with a slight female predominance. It may be solitary or multiple, the latter being an important marker for Cowden syndrome. It presents as a painless, solid nodular tumor that is slow-growing. It must be considered in the differential diagnosis of other well-circumscribed skin lesions, such as dermatofibroma, pleomorphic fibroma, sclerotic lipoma, fibrolipoma, giant cell collagenoma, benign fibrous histiocytoma, intradermal Spitz nevus and giant cell angiohistiocytoma.
storiform胶原瘤是一种罕见的肿瘤，起源于成纤维细胞的增殖，这些成纤维细胞显示I型胶原蛋白的产生增加。它通常见于面部、颈部和四肢，但也可出现在躯干、头皮，较少见的是口腔黏膜和甲床。它影响两性，女性略占优势。它可以是单发或多发，后者是考登综合征的重要标志。它表现为无痛性实性结节状肿瘤，生长缓慢。在鉴别诊断其他边界清楚的皮肤病变时必须考虑到它，如皮肤纤维瘤、多形性纤维瘤、硬化性脂肪瘤、纤维脂肪瘤、巨细胞胶原瘤、良性纤维组织细胞瘤、皮内斯皮茨痣和巨细胞血管组织细胞瘤。
