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老年癌症患者的治疗:老年医学视角

Treating older adults with cancer: geriatric perspectives.

作者信息

Klepin Heidi D, Rodin Miriam, Hurria Arti

机构信息

From the Section on Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, NC; Division of Geriatrics, Saint Louis University School of Medicine, St. Louis, MO; Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA.

出版信息

Am Soc Clin Oncol Educ Book. 2015:e544-52. doi: 10.14694/EdBook_AM.2015.35.e544.

Abstract

The proportion of older adults (age 65 and older) in oncology practices continues to increase. Older adults present with unique issues that complicate management decisions and evidence from randomized clinical trials to inform management of these patients is lacking. Despite this, principles of geriatric medicine need to be incorporated into oncology practice to provide optimal individualized care to patients. There is increasing evidence from observational studies that geriatric assessment (GA) strategies can be applied in oncology, can help predict treatment outcomes, and can inform supportive care management for older adults. In this review, we discuss the principles of GA and their use in older adults with cancer. In addition, considerations on when to refer to a geriatrician and issues related to management of vulnerable older adults will be addressed.

摘要

肿瘤学实践中老年患者(65岁及以上)的比例持续上升。老年患者存在一些独特问题,这些问题使管理决策变得复杂,而且缺乏来自随机临床试验的证据来指导这些患者的管理。尽管如此,老年医学原则仍需纳入肿瘤学实践,以便为患者提供最佳的个性化护理。越来越多的观察性研究证据表明,老年评估(GA)策略可应用于肿瘤学,有助于预测治疗结果,并可为老年患者的支持性护理管理提供参考。在本综述中,我们讨论了GA的原则及其在老年癌症患者中的应用。此外,还将探讨何时转诊至老年病专家的相关考虑因素以及与弱势老年患者管理相关的问题。

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