[New opportunities in the diagnosis of ulcerative colitis].

PURPOSE OF THE STUDY

to analyze the expression of markers of apoptosis and proliferation in patients with ulcerative colitis.

MATERIALS AND METHODS

in 80 patients with ulcerative colitis the analysis of expression of apoptosis marker BAX and proliferation marker Ki-67, as well as the cell cycle regulator p53 in biopsy materials of the mucous membrane of the colon was carried out.

THE RESULTS

decreased cell proliferative activity and increase of the apoptosis rate depending on the severity, the localization of the inflammatory process and its endoscopic activity were registered.