土耳其大学生初潮年龄与自闭症特质之间的关联。
Association between age at menarche and autistic traits in Turkish university students.
作者信息
Hergüner Arzu, Hergüner Sabri
机构信息
Child and Adolescent Psychiatry Clinic, Konya Training and Research Hospital, Necmettin Erbakan University, Konya, Turkey.
Department of Child and Adolescent Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
出版信息
Am J Hum Biol. 2016 Jan-Feb;28(1):44-7. doi: 10.1002/ajhb.22739. Epub 2015 May 20.
OBJECTIVES
The androgen theory of autism suggests that masculinizing effect of fetal androgens may play a role in the expression of autism. Recent evidence showed that excessive prenatal androgen exposure might delay age at menarche (AAM). The aim of this study was to investigate the relation between autistic traits and AAM in a sample of nonclinical female university students.
METHODS
Autistic traits were measured using the Autism Spectrum Quotient (AQ), and AAM was questioned by retrospective self-reports. The AQ was completed by 436 female university students.
RESULTS
There were significant positive correlations between AAM and AQ total and subscales measuring Social Skills, Communication, and Imagination. Subjects with above average autistic traits reported later AAM than subjects with below average autistic traits.
CONCLUSION
These findings suggest that there may be a common developmental mechanism between delayed menarche and autistic traits, possibly through elevated levels of prenatal androgens.
目的
自闭症的雄激素理论表明，胎儿雄激素的男性化作用可能在自闭症的表现中起作用。最近的证据表明，产前雄激素暴露过多可能会推迟初潮年龄（AAM）。本研究的目的是在非临床女大学生样本中调查自闭症特征与初潮年龄之间的关系。
方法
使用自闭症谱系商数（AQ）测量自闭症特征，并通过回顾性自我报告询问初潮年龄。436名女大学生完成了AQ测试。
结果
初潮年龄与AQ总分以及测量社交技能、沟通和想象力的子量表之间存在显著正相关。自闭症特征高于平均水平的受试者报告的初潮年龄比自闭症特征低于平均水平的受试者晚。
结论
这些发现表明，初潮延迟和自闭症特征之间可能存在共同的发育机制，可能是通过产前雄激素水平升高。
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