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澳大利亚自闭症谱系障碍男女孩典型青春期发育时间。

Typical Pubertal Timing in an Australian Population of Girls and Boys with Autism Spectrum Disorder.

机构信息

School of Psychology, Deakin University, 221 Burwood Highway, Burwood, VIC, 3125, Australia.

Department of Paediatrics, University of Melbourne, Parkville, Australia.

出版信息

J Autism Dev Disord. 2017 Dec;47(12):3983-3993. doi: 10.1007/s10803-017-3281-3.

Abstract

Secondary data analyses from the Longitudinal Study of Australian Children Kindergarten cohort were performed to understand any alterations in pubertal timing in Autism Spectrum Disorder (ASD) in a population sample. Timing of parent-reported pubertal events (ages 8-9, 10-11, 12-13 years), and self-report (14-15 years; N = 3454 no ASD, N = 94 with ASD) included breast development, menses, skin changes, growth spurt, body hair, deepening voice and facial hair. Survival analyses and Cox regression controlling for covariates showed no evidence of altered pubertal onset amongst males with ASD. In contrast to some past studies, there was also no difference in pubertal timing in females with ASD. These exploratory findings suggest typical puberty timing in a population representative group of young people with ASD.

摘要

对澳大利亚儿童幼儿园队列纵向研究的二次数据分析,旨在了解自闭症谱系障碍(ASD)人群样本中青春期时间的任何变化。父母报告的青春期事件(8-9 岁、10-11 岁、12-13 岁)和自我报告(14-15 岁;无 ASD 的 N=3454 人,有 ASD 的 N=94 人)包括乳房发育、月经初潮、皮肤变化、生长突增、体毛、声音变深沉和胡须生长。生存分析和 Cox 回归控制协变量显示,ASD 男性的青春期起始没有改变的证据。与过去的一些研究不同,ASD 女性的青春期时间也没有差异。这些探索性发现表明,在代表性的 ASD 年轻人人群中,青春期时间正常。

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