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经皮不可逆电穿孔治疗不可切除肝门部胆管癌（克氏瘤）：一例报告

Percutaneous Irreversible Electroporation of Unresectable Hilar Cholangiocarcinoma (Klatskin Tumor): A Case Report.

作者信息

Melenhorst Marleen C A M, Scheffer Hester J, Vroomen Laurien G P H, Kazemier Geert, van den Tol M Petrousjka, Meijerink Martijn R

机构信息

Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

Department of Surgery, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

出版信息

Cardiovasc Intervent Radiol. 2016 Jan;39(1):117-21. doi: 10.1007/s00270-015-1126-z. Epub 2015 May 21.

DOI:10.1007/s00270-015-1126-z
PMID:25994516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4689746/
Abstract

Irreversible electroporation (IRE) is a novel image-guided ablation technique that is rapidly gaining popularity in the treatment of malignant tumors located near large vessels or bile ducts. The presence of metal objects in the ablation zone, such as Wallstents, is generally considered a contraindication for IRE, because tissue heating due to power conduction may lead to thermal complications. This report describes a 66-year-old female with a Bismuth-Corlette stage IV unresectable cholangiocarcinoma with a metallic Wallstent in the common bile duct, who was safely treated with percutaneous IRE with no signs for relapse 1 year after the procedure.

摘要

不可逆电穿孔（IRE）是一种新型的图像引导消融技术，在治疗位于大血管或胆管附近的恶性肿瘤方面正迅速受到欢迎。消融区域中金属物体的存在，如Wallstent支架，通常被认为是IRE的禁忌症，因为由于电流传导导致的组织加热可能会引发热并发症。本报告描述了一名66岁女性，患有Bismuth-Corlette IV期不可切除胆管癌，胆总管内有一个金属Wallstent支架，该患者接受了经皮IRE治疗，术后1年无复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0869/4689746/5b6f23e638a0/270_2015_1126_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0869/4689746/dbf883380a64/270_2015_1126_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0869/4689746/5b6f23e638a0/270_2015_1126_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0869/4689746/dbf883380a64/270_2015_1126_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0869/4689746/5b6f23e638a0/270_2015_1126_Fig2_HTML.jpg

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Acta Radiol Short Rep. 2014 Dec 3;3(11):2047981614556409. doi: 10.1177/2047981614556409. eCollection 2014 Dec.
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Irreversible electroporation: just another form of thermal therapy?不可逆电穿孔：仅仅是热疗的另一种形式？
Prostate. 2015 Feb 15;75(3):332-5. doi: 10.1002/pros.22913. Epub 2014 Oct 18.
3
Palliation: Hilar cholangiocarcinoma.
不同经皮经肝胆道支架置入及导管引流术治疗中低位恶性胆管梗阻
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4
Irreversible Electroporation: An Emerging Immunomodulatory Therapy on Solid Tumors.不可逆电穿孔：实体瘤的一种新兴免疫调节治疗方法。
Front Immunol. 2022 Jan 7;12:811726. doi: 10.3389/fimmu.2021.811726. eCollection 2021.
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Minimally invasive image-guided therapy of primary and metastatic pancreatic cancer.原发性和转移性胰腺癌的微创影像引导治疗。
World J Gastroenterol. 2021 Jul 21;27(27):4322-4341. doi: 10.3748/wjg.v27.i27.4322.
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Sci Rep. 2020 Aug 11;10(1):13517. doi: 10.1038/s41598-020-70308-3.
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