Institute of Genetic Medicine, Howard Hughes Medical Institute, and Smilow Center for Marfan Syndrome Research, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Sci Transl Med. 2015 May 20;7(288):288fs21. doi: 10.1126/scitranslmed.aab0044.
Myofibroblast-derived αvβ1 integrin has emerged as a critical mediator of transforming growth factor-β activation in experimental models of tissue fibrosis (Reed et al., this issue).
肌成纤维细胞衍生的αvβ1 整合素已成为组织纤维化实验模型中转化生长因子-β激活的关键介质(Reed 等人,本期)。