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1
Recent progress in understanding the natural and clinical histories of the Marfan syndrome.了解马凡综合征的自然和临床病史的最新进展。
Trends Cardiovasc Med. 2016 Jul;26(5):423-8. doi: 10.1016/j.tcm.2015.12.003. Epub 2016 Jan 13.
2
The αvβ1 integrin plays a critical in vivo role in tissue fibrosis.αvβ1整合素在组织纤维化的体内过程中发挥着关键作用。
Sci Transl Med. 2015 May 20;7(288):288ra79. doi: 10.1126/scitranslmed.aaa5094.
3
One integrin to rule them all?一种整合素可以统管全局吗?
Sci Transl Med. 2015 May 20;7(288):288fs21. doi: 10.1126/scitranslmed.aab0044.
4
Beneficial Outcome of Losartan Therapy Depends on Type of FBN1 Mutation in Marfan Syndrome.氯沙坦治疗的有益结果取决于马凡综合征中FBN1突变的类型。
Circ Cardiovasc Genet. 2015 Apr;8(2):383-8. doi: 10.1161/CIRCGENETICS.114.000950. Epub 2015 Jan 22.
5
Atenolol versus losartan in children and young adults with Marfan's syndrome.阿替洛尔与氯沙坦用于患有马凡氏综合征的儿童和年轻人的比较。
N Engl J Med. 2014 Nov 27;371(22):2061-71. doi: 10.1056/NEJMoa1404731. Epub 2014 Nov 18.
6
Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.膜拉伸对β-抑制蛋白偏向性血管紧张素II 1型受体信号传导的变构调节。
J Biol Chem. 2014 Oct 10;289(41):28271-83. doi: 10.1074/jbc.M114.585067. Epub 2014 Aug 28.
7
Increased activation of latent TGF-β1 by αVβ3 in human Crohn's disease and fibrosis in TNBS colitis can be prevented by cilengitide.αVβ3 在人类克罗恩病和 TNBS 结肠炎纤维化中增加潜伏 TGF-β1 的激活可被西仑吉肽所预防。
Inflamm Bowel Dis. 2013 Dec;19(13):2829-39. doi: 10.1097/MIB.0b013e3182a8452e.
8
Shear stress activates extracellular signal-regulated kinase 1/2 via the angiotensin II type 1 receptor.切应力通过血管紧张素 II 型 1 受体激活细胞外信号调节激酶 1/2。
FASEB J. 2013 Aug;27(8):3008-16. doi: 10.1096/fj.12-222299. Epub 2013 Apr 12.
9
Integrin control of the transforming growth factor-β pathway in glioblastoma.整合素在胶质母细胞瘤中对转化生长因子-β 通路的调控。
Brain. 2013 Feb;136(Pt 2):564-76. doi: 10.1093/brain/aws351. Epub 2013 Jan 31.
10
MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.MMP-2 调节马凡综合征中的 Erk1/2 磷酸化和主动脉扩张。
Circ Res. 2012 Jun 8;110(12):e92-e101. doi: 10.1161/CIRCRESAHA.112.268268. Epub 2012 May 1.

Editorial Commentary: Understanding Marfan syndrome, or "how not to invent the light bulb".

作者信息

Jones Jeffrey A

机构信息

Division of Cardiothoracic Surgery Research, Department of Surgery, Medical University of South Carolina and the Research Service, Ralph H. Johnson Veterans Affairs Medical Center, Strom Thurmond Research Building, Charleston, SC.

出版信息

Trends Cardiovasc Med. 2016 Jul;26(5):429-32. doi: 10.1016/j.tcm.2016.02.005. Epub 2016 Feb 23.

DOI:10.1016/j.tcm.2016.02.005
PMID:27013137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4912448/
Abstract
摘要