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肝细胞癌与生物学行为相关的磁共振成像特征

MRI features of hepatocellular carcinoma related to biologic behavior.

作者信息

Cho Eun-Suk, Choi Jin-Young

机构信息

Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 135-720, Korea.

Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul 120-752, Korea.

出版信息

Korean J Radiol. 2015 May-Jun;16(3):449-64. doi: 10.3348/kjr.2015.16.3.449. Epub 2015 May 13.

DOI:10.3348/kjr.2015.16.3.449
PMID:25995679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4435980/
Abstract

Imaging studies including magnetic resonance imaging (MRI) play a crucial role in the diagnosis and staging of hepatocellular carcinoma (HCC). Several recent studies reveal a large number of MRI features related to the prognosis of HCC. In this review, we discuss various MRI features of HCC and their implications for the diagnosis and prognosis as imaging biomarkers. As a whole, the favorable MRI findings of HCC are small size, encapsulation, intralesional fat, high apparent diffusion coefficient (ADC) value, and smooth margins or hyperintensity on the hepatobiliary phase of gadoxetic acid-enhanced MRI. Unfavorable findings include large size, multifocality, low ADC value, non-smooth margins or hypointensity on hepatobiliary phase images. MRI findings are potential imaging biomarkers in patients with HCC.

摘要

包括磁共振成像（MRI）在内的影像学检查在肝细胞癌（HCC）的诊断和分期中起着至关重要的作用。最近的几项研究揭示了大量与HCC预后相关的MRI特征。在本综述中，我们讨论了HCC的各种MRI特征及其作为影像学生物标志物在诊断和预后方面的意义。总体而言，HCC的有利MRI表现为体积小、有包膜、瘤内脂肪、表观扩散系数（ADC）值高，以及在钆塞酸增强MRI的肝胆期边缘光滑或呈高信号。不利表现包括体积大、多灶性、ADC值低、边缘不光滑或在肝胆期图像上呈低信号。MRI表现是HCC患者潜在的影像学生物标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/43fb5b80c847/kjr-16-449-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/36f352634d52/kjr-16-449-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/362f6309681a/kjr-16-449-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/5d97ca812f76/kjr-16-449-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/205ef78c0eda/kjr-16-449-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/638b1c5d2367/kjr-16-449-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/6a5159dd9dc9/kjr-16-449-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/89217db0f894/kjr-16-449-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/baece6716b87/kjr-16-449-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/43fb5b80c847/kjr-16-449-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/36f352634d52/kjr-16-449-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/362f6309681a/kjr-16-449-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/5d97ca812f76/kjr-16-449-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/205ef78c0eda/kjr-16-449-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/638b1c5d2367/kjr-16-449-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/6a5159dd9dc9/kjr-16-449-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/89217db0f894/kjr-16-449-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/baece6716b87/kjr-16-449-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d2/4435980/43fb5b80c847/kjr-16-449-g009.jpg

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