Guglielmini C, Casoni I, Patracchini M, Manfredini F, Grazzi G, Ferrari M, Conconi F
Centro di Richerche Biomediche Applicate allo Sport, Universitá di Ferrara, Italy.
Int J Sports Med. 1989 Oct;10(5):352-6. doi: 10.1055/s-2007-1024927.
Hematological variables of 40 professional cyclists, all receiving intravenous iron supplementation, were followed during a 15-month period. Mean values for red blood cells (RBC), hemoglobin (Hb), and hematocrit (Ht) were significantly lower during the racing season (RS) than during the nonracing periods (NRP) (RBC: RS = 4.53 +/- 0.34 millions/mm3, NRP = 5.09 +/- 0.36 millions/mm3; line 7 of abstract: Hb: RS = 14.2 +/- 0.9 g/dl, MRS = 15.2 +/- 0.9 g/dl; Ht: RS = 40.7 +/- 2.7% NRP = 44.4 +/- 2.9%; P less than 0.001 for all). However, mean values for ferritin and mean corpuscular hemoglobin (MCH) were significantly higher during the racing season (ferritin: RS = 422 +/- 398 ng/ml, NRP = 311 +/- 321 ng/ml, P less than 0.05; MCH: RS = 31.5 +/- 1.3 pg, NRP = 30.0 +/- 1.4 pg; P less than 0.001). These results suggest that the reductions in RBC, Hb, and Ht found in professional cyclists during the racing season are not the consequence of a diminution of iron stores but rather of reduced erythropoiesis and increased RBC destruction.
对40名职业自行车运动员进行了为期15个月的跟踪研究，这些运动员均接受静脉补铁。在比赛季节（RS），红细胞（RBC）、血红蛋白（Hb）和血细胞比容（Ht）的平均值显著低于非比赛期（NRP）（RBC：RS = 4.53±0.34百万/mm³，NRP = 5.09±0.36百万/mm³；摘要第7行：Hb：RS = 14.2±0.9 g/dl，MRS = 15.2±0.9 g/dl；Ht：RS = 40.7±2.7%，NRP = 44.4±2.9%；所有P均小于0.001）。然而，在比赛季节，铁蛋白和平均红细胞血红蛋白（MCH）的平均值显著更高（铁蛋白：RS = 422±398 ng/ml，NRP = 311±321 ng/ml，P小于0.05；MCH：RS = 31.5±1.3 pg，NRP = 30.0±1.4 pg；P小于0.001）。这些结果表明，职业自行车运动员在比赛季节出现的RBC、Hb和Ht降低并非铁储备减少的结果，而是红细胞生成减少和RBC破坏增加的结果。
