Jo Young-Joon, Lim Hyung-Bin, Lee Soo-Hyun, Kim Jung-Yeul
Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Ophthalmologica. 2015;234(3):160-6. doi: 10.1159/000381788. Epub 2015 May 13.
To evaluate the effects of retinal angiography, using fluorescein and indocyanine green dyes, on optical coherence tomography (OCT) measurements.
In total, 76 eyes from 76 consecutive patients were included. Macular cube 512 × 128 combination scanning and optic disc 200 × 200 scanning using spectral-domain (SD)-OCT were performed twice, before and after retinal angiography, with fluorescein or indocyanine green. Signal strength, regional retinal thickness of the 9 Early Treatment Diabetic Retinopathy Study subfields, total macular volume, and retinal nerve fiber layer thickness obtained before and after angiography were compared. Repeatability was also investigated.
Comparing the results of OCT measured before and after retinal angiography, there was no statistically significant difference in any parameter assessed. The interclass correlation values for each measurement were all >0.808 (range 0.808-0.999).
Retinal angiography using fluorescein and indocyanine green dyes has no significant effect on OCT measurements.
评估使用荧光素和吲哚菁绿染料的视网膜血管造影对光学相干断层扫描（OCT）测量结果的影响。
共纳入76例连续患者的76只眼。在使用荧光素或吲哚菁绿进行视网膜血管造影之前和之后，使用光谱域（SD）-OCT进行两次黄斑区512×128组合扫描和视盘200×200扫描。比较血管造影前后获得的信号强度、9个早期糖尿病视网膜病变研究子区域的局部视网膜厚度、黄斑总体积和视网膜神经纤维层厚度。还研究了重复性。
比较视网膜血管造影前后OCT测量结果，所评估的任何参数均无统计学显著差异。每次测量的组内相关值均>0.808（范围0.808-0.999）。
使用荧光素和吲哚菁绿染料的视网膜血管造影对OCT测量无显著影响。
