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抑郁成年人终生自杀未遂和非自杀性自伤的童年预测因素。

Childhood predictors of lifetime suicide attempts and non-suicidal self-injury in depressed adults.

作者信息

Johnstone Jeanette M, Carter Janet D, Luty Suzanne E, Mulder Roger T, Frampton Christopher M, Joyce Peter R

机构信息

Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand Department of Psychiatry, Oregon Health & Science University, Portland, Oregon, USA

Department of Psychology, University of Canterbury, Christchurch, New Zealand.

出版信息

Aust N Z J Psychiatry. 2016 Feb;50(2):135-44. doi: 10.1177/0004867415585581. Epub 2015 May 21.

Abstract

OBJECTIVE

Adverse childhood experiences are well-recognized risk factors for a variety of mental health issues, including depression, suicide attempts and non-suicidal self-injury. However, less is known about whether childhood adversity, in the form of low parental care, overprotection and abuse, is associated with suicide attempt and non-suicidal self-injury within a sample of depressed adults.

METHOD

The sample of outpatients (n = 372) was drawn from two randomized depression trials. Childhood adversity variables, depression severity, age of first depressive episode (major depression episode onset), lifetime suicide attempt and non-suicidal self-injury were recorded at baseline. The association between variables and outcome measures was examined using partial correlations, univariate and multivariate logistic regressions.

RESULTS

Low maternal care was significantly associated with suicide attempt; low paternal care was associated with non-suicidal self-injury; overprotection was not associated with either outcome. Other risk factors for suicide attempt were major depression episode onset and baseline depression severity. Major depression episode onset was also a risk factor for non-suicidal self-injury. Abuse, regardless of how it was measured, was not significantly associated with either behaviour after adjusting for its correlations with low maternal or paternal care.

CONCLUSION

In this sample of depressed adults, the quality of ongoing, intra-familial relationships, as measured by levels of parental care, had a greater impact on suicide attempt and non-suicidal self-injury than abuse. As the findings were not a priori hypotheses, they require replication. Although the cross-sectional study design limits causal determination, the findings suggest different childhood risk factors for suicide attempt and non-suicidal self-injury and underscore the impact of low parental care on these two behaviours. These findings signal to clinicians the importance of asking specifically about suicide attempts, and non-suicidal self-injury, as well as levels of parental care in childhood. When endorsed, low parental care may be considered an important factor in contextualizing a patient's depression and potential risk for suicide and non-suicidal self-injury.

摘要

目的

童年不良经历是多种心理健康问题公认的风险因素,包括抑郁症、自杀未遂和非自杀性自伤。然而,对于以父母关爱不足、过度保护和虐待形式存在的童年逆境是否与抑郁成年人群样本中的自杀未遂和非自杀性自伤相关,人们了解较少。

方法

门诊患者样本(n = 372)来自两项随机抑郁症试验。在基线时记录童年逆境变量、抑郁严重程度、首次抑郁发作年龄(重度抑郁发作起病)、终生自杀未遂和非自杀性自伤情况。使用偏相关、单变量和多变量逻辑回归分析变量与结局指标之间的关联。

结果

母亲关爱不足与自杀未遂显著相关;父亲关爱不足与非自杀性自伤相关;过度保护与两种结局均无关联。自杀未遂的其他风险因素是重度抑郁发作起病和基线抑郁严重程度。重度抑郁发作起病也是非自杀性自伤的风险因素。在调整了与母亲或父亲关爱不足的相关性后,无论如何衡量,虐待与这两种行为均无显著关联。

结论

在这个抑郁成年人群样本中,以父母关爱水平衡量的持续的家庭内关系质量,对自杀未遂和非自杀性自伤的影响大于虐待。由于这些发现并非先验假设,需要重复验证。尽管横断面研究设计限制了因果关系的确定,但这些发现提示了自杀未遂和非自杀性自伤不同的童年风险因素,并强调了父母关爱不足对这两种行为的影响。这些发现向临床医生表明,特别询问自杀未遂、非自杀性自伤以及童年时期父母关爱水平的重要性。当得到肯定回答时,父母关爱不足可能被视为将患者的抑郁症以及自杀和非自杀性自伤潜在风险背景化的一个重要因素。

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