Dusaud Marie, Bayoud Younes, Desfemmes François-Régis, Molimard Benoît, Durand Xavier
Department of Urology, Military Hospital of Val de Grâce, 74 boulevard de Port Royal, 75005 Paris, France.
Case Rep Urol. 2015;2015:160560. doi: 10.1155/2015/160560. Epub 2015 Apr 27.
A 45-year-old man with a left testis tumor with a 25 mm para-aortic lymph node swelling, multiple bilateral pulmonary metastases, bilateral pulmonary embolism, and inferior vena cava (IVC) thrombus underwent a radical orchidectomy in our institution. The thrombus extended from the left gonadal vein to the left renal vein to the IVC. The fluorine-18 fluorodeoxyglucose (f-FDG) positron emission tomography (PET) computerized tomography (CT) demonstrated a hypermetabolic focus in the retroperitoneum and in the IVC thrombus. Before orchidectomy only lactate dehydrogenase (LDH) was high but all the serum tumor markers increased postoperatively. The tumor was staged pT1N2M1aS1, which was an intermediate prognosis, based on the International Germ Cell Cancer Collaborative Group consensus (IGCCCG). After 4 courses of bleomycin, etoposide, and cisplatin (BEP) chemotherapy the patient's tumor markers normalized and the thrombus disappeared. There was only one residual retroperitoneal lymph node M1. Retroperitoneal lymph node dissection was performed. The pathological examination revealed only necrotic tissues. The patient has been disease-free since surgery.
一名45岁男性,患有左侧睾丸肿瘤,伴有25毫米的主动脉旁淋巴结肿大、多发双侧肺转移、双侧肺栓塞以及下腔静脉(IVC)血栓形成,在我院接受了根治性睾丸切除术。血栓从左性腺静脉延伸至左肾静脉再到下腔静脉。氟-18氟脱氧葡萄糖(f-FDG)正电子发射断层扫描(PET)计算机断层扫描(CT)显示腹膜后和下腔静脉血栓中有高代谢灶。睾丸切除术前仅乳酸脱氢酶(LDH)升高,但术后所有血清肿瘤标志物均升高。根据国际生殖细胞癌协作组共识(IGCCCG),肿瘤分期为pT1N2M1aS1,属于中期预后。经过4个疗程的博来霉素、依托泊苷和顺铂(BEP)化疗后,患者的肿瘤标志物恢复正常,血栓消失。仅残留一个腹膜后淋巴结转移灶(M1)。遂进行了腹膜后淋巴结清扫术。病理检查仅发现坏死组织。该患者自手术以来一直无病生存。