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睾丸癌伴恶性肿瘤血栓形成的罕见表现:一例报告

Rare Presentation of Testicular Cancer With Malignant Tumor Thrombus: A Case Report.

作者信息

Khushaym Abdulaziz H, Aljeeran Noora, Alabbasi Lana

机构信息

Urology, King Hamad University Hospital, Busaiteen, BHR.

Internal Medicine, King Hamad University Hospital, Busaiteen, BHR.

出版信息

Cureus. 2024 Sep 21;16(9):e69857. doi: 10.7759/cureus.69857. eCollection 2024 Sep.

Abstract

In rare cases, testicular cancer can metastasize to the inferior vena cava (IVC) through a tumor thrombus, significantly worsening the prognosis. This case report describes the management and the outcome of a rare presentation of testicular cancer. A 38-year-old male presented with a testicular mass and was found to have a mixed germ cell tumor with predominantly yolk sac components. Imaging after the initial orchiectomy revealed an IVC tumor thrombus extending from the left renal vein, as well as retroperitoneal and pulmonary metastases. The patient was urgently started on anticoagulation and underwent three cycles of BEP chemotherapy (bleomycin, etoposide, and cisplatin), which led to complete metabolic and radiographic regression of the metastatic disease.

摘要

在罕见情况下,睾丸癌可通过肿瘤血栓转移至下腔静脉(IVC),显著恶化预后。本病例报告描述了一例罕见的睾丸癌表现的治疗及结果。一名38岁男性因睾丸肿块就诊,被诊断为主要由卵黄囊成分组成的混合性生殖细胞肿瘤。初次睾丸切除术后的影像学检查显示下腔静脉肿瘤血栓从左肾静脉延伸,同时伴有腹膜后和肺部转移。患者紧急开始抗凝治疗,并接受了三个周期的BEP化疗(博来霉素、依托泊苷和顺铂),这导致转移性疾病完全代谢缓解和影像学消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1d4/11493207/dc4a61d9e6d4/cureus-0016-00000069857-i01.jpg

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