Lai Yu-Shu, Chen Wen-Chuan, Huang Chang-Hung, Cheng Cheng-Kung, Chan Kam-Kong, Chang Ting-Kuo
Orthopaedic Device Research Center, National Yang-Ming University, Taipei, Taiwan.
Department of Medical Research, Mackay Memorial Hospital, New Taipei City, Taiwan.
PLoS One. 2015 May 22;10(5):e0127293. doi: 10.1371/journal.pone.0127293. eCollection 2015.
Surgical reconstruction is generally recommended for posterior cruciate ligament (PCL) injuries; however, the use of grafts is still a controversial problem. In this study, a three-dimensional finite element model of the human tibiofemoral joint with articular cartilage layers, menisci, and four main ligaments was constructed to investigate the effects of graft strengths on knee kinematics and in-situ forces of PCL grafts. Nine different graft strengths with stiffness ranging from 0% (PCL rupture) to 200%, in increments of 25%, of an intact PCL's strength were used to simulate the PCL reconstruction. A 100 N posterior tibial drawer load was applied to the knee joint at full extension. Results revealed that the maximum posterior translation of the PCL rupture model (0% stiffness) was 6.77 mm in the medial compartment, which resulted in tibial internal rotation of about 3.01°. After PCL reconstruction with any graft strength, the laxity of the medial tibial compartment was noticeably improved. Tibial translation and rotation were similar to the intact knee after PCL reconstruction with graft strengths ranging from 75% to 125% of an intact PCL. When the graft's strength surpassed 150%, the medial tibia moved forward and external tibial rotation greatly increased. The in-situ forces generated in the PCL grafts ranged from 13.15 N to 75.82 N, depending on the stiffness. In conclusion, the strength of PCL grafts have has a noticeable effect on anterior-posterior translation of the medial tibial compartment and its in-situ force. Similar kinematic response may happen in the models when the PCL graft's strength lies between 75% and 125% of an intact PCL.
后交叉韧带(PCL)损伤一般建议进行手术重建;然而,移植物的使用仍然是一个有争议的问题。在本研究中,构建了一个包含关节软骨层、半月板和四条主要韧带的人体胫股关节三维有限元模型,以研究移植物强度对膝关节运动学及PCL移植物原位力的影响。使用九种不同强度的移植物,其刚度范围从0%(PCL断裂)到完整PCL强度的200%,以25%的增量递增,来模拟PCL重建。在膝关节完全伸展时,对其施加100 N的胫骨后向抽屉负荷。结果显示,PCL断裂模型(0%刚度)在内侧间室的最大后向平移为6.77 mm,导致胫骨内旋约3.01°。使用任何强度的移植物进行PCL重建后,内侧胫股间室的松弛度均有明显改善。当移植物强度在完整PCL强度的75%至125%范围内进行PCL重建后,胫骨的平移和旋转与完整膝关节相似。当移植物强度超过150%时,内侧胫骨向前移动,胫骨外旋大幅增加。PCL移植物产生的原位力范围为13.15 N至75.82 N,具体取决于刚度。总之,PCL移植物的强度对内侧胫股间室的前后平移及其原位力有显著影响。当PCL移植物强度在完整PCL强度的75%至125%之间时,模型中可能会出现类似的运动学反应。