Masuda Taisei, Oh Minho, Kobayashi Equo
Department of Materials Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, S8-18, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8552, Japan.
Materials (Basel). 2024 Jul 13;17(14):3470. doi: 10.3390/ma17143470.
The fabrication of Ti-Mg composite biomaterials was investigated using spark plasma sintering (SPS) with varying Mg contents and sintering pressures. The effects of powder mixing, Mg addition, and sintering pressure on the microstructure and mechanical properties of the composite materials were systematically analyzed. Uniform dispersion of Mg within the Ti matrix was achieved, confirming the efficacy of ethanol-assisted ball milling for consistent mixing. The Young's modulus of the composite materials exhibited a linear decrease with increasing Mg content, with Ti-30vol%Mg and Ti-50vol%Mg demonstrating reduced modulus values compared to pure Ti. Based on density measurements, compression tests, and Young's modulus results, it was determined that the sinterability of Ti-30vol%Mg saturates at a sintering pressure of approximately 50 MPa. Moreover, our immersion tests in physiological saline underscore the profound significance of our findings. Ti-30vol%Mg maintained compressive strength above that of cortical bone for 6-to-10 days, with mechanical integrity improving under higher sintering pressures. These findings mark a significant leap towards the development of Ti-Mg composite biomaterials with tailored mechanical properties, thereby enhancing biocompatibility and osseointegration for a wide range of biomedical applications.
采用放电等离子烧结（SPS）法，在不同镁含量和烧结压力条件下对钛-镁复合生物材料的制备进行了研究。系统分析了粉末混合、镁添加量和烧结压力对复合材料微观结构和力学性能的影响。镁在钛基体中实现了均匀分散，证实了乙醇辅助球磨在均匀混合方面的有效性。复合材料的杨氏模量随镁含量增加呈线性下降，与纯钛相比，含30体积%镁和50体积%镁的钛复合材料模量值降低。基于密度测量、压缩试验和杨氏模量结果，确定含30体积%镁的钛复合材料在约为MPa的烧结压力下烧结性达到饱和。此外，我们在生理盐水中的浸泡试验突出了我们研究结果的深远意义。含30体积%镁的钛复合材料在6至10天内保持高于皮质骨的抗压强度，在较高烧结压力下力学完整性得到改善。这些发现标志着在开发具有定制力学性能的钛-镁复合生物材料方面取得了重大飞跃，从而增强了生物相容性和骨整合能力，可用于广泛的生物医学应用。
