Suppr超能文献

基于胶片的机器人放射外科治疗剂量验证:调试与验证

Film-based delivery quality assurance for robotic radiosurgery: Commissioning and validation.

作者信息

Blanck Oliver, Masi Laura, Damme Marie-Christin, Hildebrandt Guido, Dunst Jürgen, Siebert Frank-Andre, Poppinga Daniela, Poppe Björn

机构信息

Universitätsklinikum Schleswig-Holstein, Klinik für Strahlentherapie, Kiel, Germany; Saphir Radiochirurgie Zentrum Norddeutschland, Güstrow, Germany.

IFCA, Department of Medical Physics and Radiation Oncology, Firenze, Italy.

出版信息

Phys Med. 2015 Jul;31(5):476-83. doi: 10.1016/j.ejmp.2015.05.001. Epub 2015 May 21.

Abstract

PURPOSE

Robotic radiosurgery demands comprehensive delivery quality assurance (DQA), but guidelines for commissioning of the DQA method is missing. We investigated the stability and sensitivity of our film-based DQA method with various test scenarios and routine patient plans. We also investigated the applicability of tight distance-to-agreement (DTA) Gamma-Index criteria.

METHODS AND MATERIAL

We used radiochromic films with multichannel film dosimetry and re-calibration and our analysis was performed in four steps: 1) Film-to-plan registration, 2) Standard Gamma-Index criteria evaluation (local-pixel-dose-difference ≤2%, distance-to-agreement ≤2 mm, pass-rate ≥90%), 3) Dose distribution shift until maximum pass-rate (Maxγ) was found (shift acceptance <1 mm), and 4) Final evaluation with tight DTA criteria (≤1 mm). Test scenarios consisted of purposefully introduced phantom misalignments, dose miscalibrations, and undelivered MU. Initial method evaluation was done on 30 clinical plans.

RESULTS

Our method showed similar sensitivity compared to the standard End-2-End-Test and incorporated an estimate of global system offsets in the analysis. The simulated errors (phantom shifts, global robot misalignment, undelivered MU) were detected by our method while standard Gamma-Index criteria often did not reveal these deviations. Dose miscalibration was not detected by film alone, hence simultaneous ion-chamber measurement for film calibration is strongly recommended. 83% of the clinical patient plans were within our tight DTA tolerances.

CONCLUSION

Our presented methods provide additional measurements and quality references for film-based DQA enabling more sensitive error detection. We provided various test scenarios for commissioning of robotic radiosurgery DQA and demonstrated the necessity to use tight DTA criteria.

摘要

目的

机器人放射外科手术需要全面的剂量输送质量保证(DQA),但缺乏DQA方法调试的指南。我们通过各种测试场景和常规患者计划研究了基于胶片的DQA方法的稳定性和敏感性。我们还研究了严格的距离一致性(DTA)伽马指数标准的适用性。

方法和材料

我们使用具有多通道胶片剂量测定和重新校准功能的放射变色胶片,分析分四个步骤进行:1)胶片与计划配准,2)标准伽马指数标准评估(局部像素剂量差异≤2%,距离一致性≤2毫米,通过率≥90%),3)剂量分布偏移直至找到最大通过率(Maxγ)(偏移接受度<1毫米),4)使用严格的DTA标准(≤1毫米)进行最终评估。测试场景包括故意引入的体模错位、剂量校准错误和未输送的监测单位(MU)。对30个临床计划进行了初始方法评估。

结果

与标准的端到端测试相比,我们的方法显示出相似的敏感性,并在分析中纳入了全局系统偏移的估计。我们的方法检测到了模拟误差(体模移位、全局机器人错位、未输送的MU),而标准伽马指数标准通常未显示这些偏差。仅通过胶片无法检测到剂量校准错误,因此强烈建议同时进行离子室测量以进行胶片校准。83%的临床患者计划在我们严格的DTA公差范围内。

结论

我们提出的方法为基于胶片的DQA提供了额外的测量和质量参考,能够实现更灵敏的误差检测。我们提供了各种用于机器人放射外科手术DQA调试的测试场景,并证明了使用严格DTA标准的必要性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验