Firestone A R, Graves C N, Feagin F F
School of Dentistry, University of Alabama, Birmingham.
J Periodontol. 1989 Nov;60(11):624-7. doi: 10.1902/jop.1989.60.11.624.
To study the ability of bacteria associated with coronal caries to initiate root surface caries, a rat model was used. Root surfaces were exposed by gingivectomy in rats fed a caries-promoting diet and orally inoculated with either Actinomyces viscosus M-100, Streptococcus sobrinus (mutans) 6715, or both. A fourth group received a diet containing antibiotics. The animals were sacrificed 64 days following the gingivectomy performed on the right molar quadrants. Gingivectomy significantly increased exposed lingual root length and root caries incidence. There were no caries on non-gingivectomy root surfaces. Root surface caries incidence in the groups inoculated with A. viscosus and A. viscosus plus S. sobrinus did not differ. For both these groups, root caries incidence was significantly greater than that for the group inoculated with S. sobrinus alone. Root caries incidence in this latter group did not differ from that in the control group.
为研究与冠龋相关的细菌引发根面龋的能力，采用了大鼠模型。对喂食致龋饮食的大鼠进行牙龈切除术以暴露根面，并经口接种粘性放线菌M - 100、远缘链球菌（变形链球菌）6715或两者。第四组给予含抗生素的饮食。在右侧磨牙象限进行牙龈切除术后64天处死动物。牙龈切除术显著增加了暴露的舌侧根长度和根龋发生率。未进行牙龈切除术的根面无龋。接种粘性放线菌组以及接种粘性放线菌加远缘链球菌组的根面龋发生率无差异。对于这两组，根龋发生率均显著高于仅接种远缘链球菌的组。后一组的根龋发生率与对照组无差异。
