Alvaro-Gracia J M, Humbria A, García-Vicuña R, Ariza A, García-Vadillo A, Laffón A
Rheumatology Section, Hospital de la Princesa, Universidad Autónoma de Madrid, Spain.
J Rheumatol. 1989 Nov;16(11):1486-8.
An 18-year-old woman with tetrasomy-X (48,XXXX karyotype) who developed systemic lupus erythematosus is described. This is, to our knowledge, the first recorded case of this association. The occurrence of autoimmune disorders in patients with chromosomal aberrations is discussed.
本文描述了一名患有X染色体四体综合征（核型为48,XXXX）且患系统性红斑狼疮的18岁女性。据我们所知，这是该关联的首例记录病例。文中还讨论了染色体畸变患者自身免疫性疾病的发生情况。
