Inomata M, Yamada A, Kuroda M, Fukuda K, Kasakura S, Tanada S, Shimada H, Takashima H
Rinsho Byori. 1989 Oct;37(10):1155-60.
This study evaluated a modified latex agglutination inhibitory reaction method for the quantitation of urinary estriol in women during normal and abnormal pregnancy. The urinary levels of estriol in pregnant women measured by this method correlated with urinary and serum levels measured by radioimmunoassay. The urinary level of estriol rose during pregnancy and reached a peak at the time of delivery, after which it returned to the control level in a few days. In contrast, the urinary level of estriol in women with abnormal pregnancy did not rise during pregnancy. This method is useful to detect impaired function of the placenta in pregnant women.
本研究评估了一种改良的乳胶凝集抑制反应方法，用于定量检测正常和异常妊娠期间女性尿中雌三醇的含量。用该方法测得的孕妇尿中雌三醇水平与放射免疫法测得的尿和血清水平相关。孕期尿中雌三醇水平升高，并在分娩时达到峰值，之后在几天内恢复到对照水平。相比之下，异常妊娠女性的尿中雌三醇水平在孕期并未升高。该方法有助于检测孕妇胎盘功能受损情况。
