Kono H, Furuhashi N, Fukaya T, Shinkawa O, Takahashi T, Tsujiei M, Yajima A
Tohoku J Exp Med. 1987 Jun;152(2):129-32.
We measured maternal serum unconjugated estriol (SUE3) levels in 244 cases (218 cases with labor and 26 without labor) and investigated the relationships among several obstetrical factors and SUE3 levels. There was no significant difference in the SUE3 level between the group with labor and the group without labor. However, the SUE3 level decreased gradually with prolonged duration of labor in multipara. There were significant positive correlations between the SUE3 levels and birth weights (n = 82, r = 0.375, p less than 0.01) or placental weights (n = 82, r = 0.381, p less than 0.01) in the multipara with labor. The SUE3 levels of fetal distress cases (n = 30, 20.0 +/- 8.6 ng/ml) were significantly (p less than 0.05) lower than those without fetal distress (n = 188, 24.5 +/- 9.7 ng/ml). These data suggest that maternal SUE3 might have been affected with feto-placental function, even after the onset of labor SUE3 levels decrease with prolonged duration of labor.
我们检测了244例孕妇（218例已分娩，26例未分娩）的母血游离雌三醇（SUE3）水平，并研究了几种产科因素与SUE3水平之间的关系。已分娩组和未分娩组的SUE3水平无显著差异。然而，经产妇的SUE3水平随着产程延长而逐渐下降。在已分娩的经产妇中，SUE3水平与出生体重（n = 82，r = 0.375，p<0.01）或胎盘重量（n = 82，r = 0.381，p<0.01）之间存在显著正相关。胎儿窘迫病例（n = 30，20.0±8.6 ng/ml）的SUE3水平显著低于（p<0.05）无胎儿窘迫的病例（n = 188，24.5±9.7 ng/ml）。这些数据表明，母血SUE3可能受胎儿-胎盘功能的影响，即使在分娩开始后，SUE3水平也会随着产程延长而下降。
