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[一种用于孕期尿雌三醇半定量测定的快速(3分钟)乳胶凝集抑制试验(作者译)]

[A fast (3 minutes) latexagglutination inhibition test for semiquantitative determination of urinary estriol in pregnancy (author's transl)].

作者信息

Bieglmayer C, Kemeter P, Feichtinger W, Szalay S

出版信息

Z Geburtshilfe Perinatol. 1982 Apr-May;186(2):76-9.

PMID:7202300
Abstract

Urine samples from 176 healthy women between 29th and 40th week of gestation were analyzed by a test kit. Estrotec Slide Test, which offers a simple and fast test performance for estriol in pregnancy urine. The mechanism of this test system is based on a competitive latex agglutination inhibition reaction. The correlation between Estrotec Slide Test and estriol levels assayed in the same urine samples by a chemical method was r = 0,83. Variation of estriol determinations from urine and estriol levels in serum samples of women at the end of gestation measured by a radioimmunologic method was about 20% for all test principles examinated. The Estrotec Slide Test was proved to be a fast, semiquantitative method. The simple assay procedure itself imposes limits to the information available from it.

摘要

使用检测试剂盒对176名妊娠29至40周的健康女性的尿液样本进行了分析。采用Estrotec玻片试验,该试验对妊娠尿液中的雌三醇检测简便快捷。此检测系统的机制基于竞争性乳胶凝集抑制反应。Estrotec玻片试验与用化学方法在相同尿液样本中检测的雌三醇水平之间的相关性为r = 0.83。对于所有检测原理,通过放射免疫法测定的妊娠末期女性尿液中雌三醇测定值与血清样本中雌三醇水平的差异约为20%。Estrotec玻片试验被证明是一种快速的半定量方法。简单的检测程序本身限制了从中获得的信息量。

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