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11C-胆碱和 18F-FDG PET/CT 在副瘤综合征背景下隐匿性前列腺癌的检测中的应用。

11C-Choline and 18F-FDG PET/CT in the Detection of Occult Prostate Cancer in the Context of a Paraneoplastic Syndrome.

机构信息

From the Department of Nuclear Medicine, Marqués de Valdecilla University Hospital, University of Cantabria, Santander, Spain.

出版信息

Clin Nucl Med. 2015 Aug;40(8):695-6. doi: 10.1097/RLU.0000000000000826.

DOI:10.1097/RLU.0000000000000826
PMID:26018697
Abstract

In a 73-year-old man, an occult neoplasm was suspected after 2 consecutive deep venous thrombosis, the latter under anticoagulant therapy and previous axonopathy. After normal CT and MRI findings, a requested (18)F-FDG PET/CT showed a focal uptake in the prostate. Because FDG uptake in the prostate is infrequent, a (11)C-choline PET/CT was indicated revealing a focal uptake in the same location. No other abnormalities were detected in the rest of the body. A guided biopsy by ultrasonography was performed revealing a prostate carcinoma and inflammation in both prostatic lobes.

摘要

在一位 73 岁男性中,在连续两次深静脉血栓形成后,考虑存在隐匿性肿瘤,后者正在接受抗凝治疗,且之前存在轴索性神经病。在 CT 和 MRI 检查结果正常后,我们建议进行(18)F-FDG PET/CT 检查,结果显示前列腺局灶性摄取。由于前列腺中 FDG 摄取不常见,因此进行了(11)C-胆碱 PET/CT 检查,结果显示同一部位存在局灶性摄取。在身体的其他部位未发现其他异常。通过超声引导进行了活检,结果显示前列腺癌和两个前列腺叶的炎症。

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