From the Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing, China.
Clin Nucl Med. 2015 Jul;40(7):e357-62. doi: 10.1097/RLU.0000000000000808.
This study was performed to develop a new formula to estimate the renal depth in both children and adults; then compare the new formula with previously published formulas.
Renal depth and total thickness (T, cm) of the body at the level of the kidneys were measured by CT in 113 children and 246 adults. Their sex, age, height (H, cm), and weight (W, kg) were recorded. Multiple stepwise linear regression analysis were conducted, using data from children and adults together. The 359 cases were divided into 2 random groups, of which, the first group was used to derive a regressive formula, and the second was used to verify the formula and compare the formula with previously published formulas in different groups.
Multiple stepwise linear regression analysis showed that the important variable in estimating the depth of each kidney was the ratio of body weight (W, kg) to body height (H, cm) and the total thickness (T, cm) of the body at the level of the kidneys. The new formula was as follows: for right renal depth (cm) = 0.22 × T + 7.714 × W/H-0.331 (r = 0.95), and for left renal depth (cm) = 0.238 × T + 6.553 × W/H-0.618 (r = 0.95). It is better than the other four formulas in different groups, especially in children and W/H ≤ 0.30 (in adults) groups.
We first introduced T into renal depth estimation formula and established the new formula. It has a better performance than the other four formulas in different groups. The new formula provided reliable and accurate renal depth and may contribute to improving the methods used to estimate renal function from radionuclide renography.
本研究旨在建立一个新的公式来估算儿童和成人的肾脏深度，并与以往发表的公式进行比较。
通过 CT 对 113 名儿童和 246 名成人的肾脏水平的肾脏深度和身体总厚度（T，cm）进行测量，并记录其性别、年龄、身高（H，cm）和体重（W，kg）。使用儿童和成人的数据进行多元逐步线性回归分析。将 359 例患者随机分为 2 组，其中第 1 组用于推导回归公式，第 2 组用于验证公式，并比较不同组中公式与以往发表的公式。
多元逐步线性回归分析显示，估计每个肾脏深度的重要变量是体重（W，kg）与身高（H，cm）的比值和肾脏水平的身体总厚度（T，cm）。新公式如下：右肾深度（cm）=0.22×T+7.714×W/H-0.331（r=0.95），左肾深度（cm）=0.238×T+6.553×W/H-0.618（r=0.95）。与其他四个公式相比，它在不同组中表现更好，特别是在儿童和 W/H≤0.30（成人）组中。
我们首次将 T 引入肾脏深度估计公式，并建立了新公式。与其他四个公式相比，它在不同组中表现更好，提供了更可靠和准确的肾脏深度，并可能有助于改进放射性核素肾图法估计肾功能的方法。
