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滑石粉胸膜固定术，PET/CT显示18F-FDG摄取强烈但68Ga-DOTA-TATE无摄取。

Talc Pleurodesis With Intense 18F-FDG Activity But No 68Ga-DOTA-TATE Activity on PET/CT.

作者信息

Papadakis Georgios Z, Millo Corina, Bagci Ulas, Patronas Nicholas J, Stratakis Constantine A

机构信息

From the *Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center; †Division of Nuclear Medicine, RAD&IS, Clinical Center, National Institutes of Health; ‡Center for Research in Computer Vision, University of Central Florida, Orlando, FL; and §Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, MD.

出版信息

Clin Nucl Med. 2015 Oct;40(10):819-20. doi: 10.1097/RLU.0000000000000807.

DOI:10.1097/RLU.0000000000000807

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4564300/

Abstract

Talc pleurodesis (TP) is a technique, widely employed in the management of patients with persistent pleural effusions or pneumothoraces not amenable to other treatment options. It is well documented that talc deposits produce areas of highly increased F-FDG uptake, because of talc-induced inflammation. We present a case of a patient with history of TP who was evaluated with both F-FDG and Ga-DOTA-TATE. The hypermetabolic area seen on F-FDG-PET-CT in the region of talc placement showed no uptake by Ga-DOTA-TATE, suggesting the potential role of Ga-DOTA-TATE-PET-CT in elucidating F-FDG-postitive lesions in patients with history of both neuroendocrine malignancy and TP.

摘要

滑石粉胸膜固定术（TP）是一种广泛应用于治疗持续性胸腔积液或气胸且不适于其他治疗方案患者的技术。有充分文献记载，由于滑石粉引起的炎症，滑石粉沉积会导致F-FDG摄取显著增加的区域。我们报告一例有TP病史的患者，该患者接受了F-FDG和Ga-DOTA-TATE检查。在滑石粉植入区域的F-FDG-PET-CT上看到的高代谢区域未被Ga-DOTA-TATE摄取，这表明Ga-DOTA-TATE-PET-CT在阐明有神经内分泌恶性肿瘤和TP病史患者的F-FDG阳性病变方面具有潜在作用。