Kheirbek Raya E, Fletcher Ross D, Bakitas Marie A, Fonarow Gregg C, Parvataneni Sridivya, Bearden Donna, Bailey Frank A, Morgan Charity J, Singh Steven, Blackman Marc R, Zile Michael R, Patel Kanan, Ahmed Momanna B, Tucker Rodney O, Brown Cynthia J, Love Thomas E, Aronow Wilbert S, Roseman Jeffrey M, Rich Michael W, Allman Richard M, Ahmed Ali
From the Veterans Affairs Medical Center, Washington, DC (R.E.K., R.D.F., S.S., M.R.B., A.A.); Department of Medicine, George Washington University, Washington, DC (R.E.K., M.R.B.); Department of Medicine, Georgetown University, Washington, DC (R.D.F., S.S., M.R.B., A.A.); School of Nursing (M.A.B.) and Departments of Medicine (M.A.B., D.B., M.B.A., R.O.T., C.J.B., A.A.), Biostatistics (C.J.M.), and Epidemiology (J.M.R.), University of Alabama at Birmingham; Department of Medicine, University of California, Los Angeles (G.C.F.); Department of Medicine, East Tennessee State University, Johnson City (S.P.); Department of Medicine, University of Colorado, Denver (F.A.B.); Department of Medicine, Medical University of South Carolina, Charleston (M.R.Z.); Department of Medicine, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC (M.R.Z.); Department of Medicine, University of California, San Francisco (K.P.); Department of Medicine, Veterans Affairs Medical Center, Birmingham, AL (C.J.B.); Department of Medicine, Case Western Reserve University, Cleveland, OH (T.E.L.); Department of Medicine, New York Medical College, Valhalla (W.S.A.); Department of Medicine, Washington University, St. Louis, MO (M.W.R.); and Geriatrics and Extended Care Services, Department of Veterans Affairs, Washington, DC (R.M.A.).
Circ Heart Fail. 2015 Jul;8(4):733-40. doi: 10.1161/CIRCHEARTFAILURE.115.002153. Epub 2015 May 27.
Heart failure (HF) is the leading cause for hospital readmission. Hospice care may help palliate HF symptoms but its association with 30-day all-cause readmission remains unknown.
Of the 8032 Medicare beneficiaries hospitalized for HF in 106 Alabama hospitals (1998-2001), 182 (2%) received discharge hospice referrals. Of the 7850 patients not receiving hospice referrals, 1608 (20%) died within 6 months post discharge (the hospice-eligible group). Propensity scores for hospice referral were estimated for each of the 1790 (182+1608) patients and were used to match 179 hospice-referral patients with 179 hospice-eligible patients who were balanced on 28 baseline characteristics (mean age, 79 years; 58% women; 18% non-white). Overall, 22% (1742/8032) died in 6 months, of whom 8% (134/1742) received hospice referrals. Among the 358 matched patients, 30-day all-cause readmission occurred in 5% and 41% of hospice-referral and hospice-eligible patients, respectively (hazard ratio associated with hospice referral, 0.12; 95% confidence interval, 0.06-0.24). Hazard ratios (95% confidence intervals) for 30-day all-cause readmission associated with hospice referral among the 126 patients who died and 232 patients who survived 30-day post discharge were 0.03 (0.04-0.21) and 0.17 (0.08-0.36), respectively. Although 30-day mortality was higher in the hospice referral group (43% versus 27%), it was similar at 90 days (64% versus 67% among hospice-eligible patients).
A discharge hospice referral was associated with lower 30-day all-cause readmission among hospitalized patients with HF. However, most patients with HF who died within 6 months of hospital discharge did not receive a discharge hospice referral.
心力衰竭(HF)是医院再入院的主要原因。临终关怀可能有助于缓解HF症状,但其与30天全因再入院的关联尚不清楚。
在阿拉巴马州106家医院(1998 - 2001年)因HF住院的8032名医疗保险受益人中,182名(2%)接受了出院时的临终关怀转诊。在7850名未接受临终关怀转诊的患者中,1608名(20%)在出院后6个月内死亡(符合临终关怀条件的组)。为1790名(182 + 1608)患者中的每一位估计临终关怀转诊的倾向得分,并用于将179名接受临终关怀转诊的患者与179名符合临终关怀条件的患者进行匹配,这些患者在28项基线特征上达到平衡(平均年龄79岁;58%为女性;18%为非白人)。总体而言,22%(1742 / 8032)在6个月内死亡,其中8%(134 / 1742)接受了临终关怀转诊。在358名匹配患者中,接受临终关怀转诊和符合临终关怀条件的患者30天全因再入院率分别为5%和41%(与临终关怀转诊相关的风险比为0.12;95%置信区间为0.06 - 0.24)。在126名死亡患者和出院后30天存活的232名患者中,与临终关怀转诊相关的30天全因再入院的风险比(95%置信区间)分别为0.03(0.04 - 0.21)和0.17(0.08 - 0.36)。尽管临终关怀转诊组的30天死亡率较高(43%对27%),但90天时相似(符合临终关怀条件的患者中分别为64%对67%)。
出院时的临终关怀转诊与HF住院患者较低的30天全因再入院率相关。然而,大多数在出院后6个月内死亡的HF患者未接受出院时的临终关怀转诊。