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局灶性手部肌张力障碍的实用管理方法。

A practical approach to management of focal hand dystonia.

作者信息

Pandey Sanjay

机构信息

Department of Neurology, Room No. 507, Academic Block, Govind Ballabh Pant Hospital, New Delhi, India.

出版信息

Ann Indian Acad Neurol. 2015 Apr-Jun;18(2):146-53. doi: 10.4103/0972-2327.156563.

Abstract

Dystonia can be focal, segmental, multifocal, generalized, or hemidystonia. Focal dystonia is localized to a specific part of the body. Overall upper limb is more commonly involved in focal dystonia than lower limb and since it starts from hand, focal hand dystonia (FHD) is a more accepted terminology. Writer's cramp and musician dystonia are commonest types of FHD. Typically this dystonia is task specific, but in some patients this specificity may be lost over a period of time. Segmental or generalized dystonia may also start as FHD, so a detailed clinical assessment is required, which should be supplemented by relevant investigations. Treatment includes oral medications, injection botulinum toxin, neurosurgery including neurostimulation, and rehabilitation. Role of injection botulinum toxin has been extensively studied in writer's cramp patients and found to be effective; however, selection of muscles and techniques of injection are crucial in getting best results.

摘要

肌张力障碍可分为局灶性、节段性、多灶性、全身性或偏侧性肌张力障碍。局灶性肌张力障碍局限于身体的特定部位。在局灶性肌张力障碍中,上肢总体上比下肢更常受累,并且由于它始于手部,所以局灶性手部肌张力障碍(FHD)是更被认可的术语。书写痉挛和音乐家肌张力障碍是FHD最常见的类型。通常这种肌张力障碍是任务特异性的,但在一些患者中,这种特异性可能会随着时间的推移而丧失。节段性或全身性肌张力障碍也可能始于FHD,因此需要进行详细的临床评估,并辅以相关检查。治疗方法包括口服药物、注射肉毒杆菌毒素、包括神经刺激在内的神经外科手术以及康复治疗。注射肉毒杆菌毒素在书写痉挛患者中的作用已得到广泛研究并被发现是有效的;然而,肌肉的选择和注射技术对于获得最佳效果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c49a/4445187/d50095c0acc4/AIAN-18-146-g008.jpg

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本文引用的文献

1
Hairdresser's Dystonia: An Unusual Occupational Dystonia.美发师肌张力障碍:一种不寻常的职业性肌张力障碍。
Tremor Other Hyperkinet Mov (N Y). 2013 Dec 4;3. doi: 10.7916/D87S7MGH. eCollection 2013.
3
Motor and Sensory Dysfunction in Musician's Dystonia.音乐家肌张力障碍的运动和感觉功能障碍。
Curr Neuropharmacol. 2013 Jan;11(1):41-7. doi: 10.2174/157015913804999531.
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Botulinum toxin's axonal transport from periphery to the spinal cord.肉毒毒素从外周向脊髓的轴突运输。
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9
Botulinum toxin for treatment of dystonia.肉毒毒素治疗肌张力障碍。
Eur J Neurol. 2010 Jul;17 Suppl 1:88-96. doi: 10.1111/j.1468-1331.2010.03058.x.

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