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[肉毒杆菌毒素治疗书写痉挛]

[Treatment of writer's cramp with botulinum toxin].

作者信息

Amthor K F, Skjelland M, Heier M S

机构信息

Nevrologisk avdeling, Ullevål sykehus, Oslo.

出版信息

Tidsskr Nor Laegeforen. 1994 Jun 20;114(16):1830-1.

PMID:8079300
Abstract

Writer's cramp is a focal dystonia that is resistant to most treatment regimens. This article describes two patients with writer's cramp who were successfully treated with botulinum toxin injections into the forearm muscles. Transient weakness due to the effect of botulinum toxin was registered in the injected muscles. No other side effects were observed. The beneficial effect of a single injection lasted from three to four months and could be reproduced by repeated injections over a three year follow-up period. We conclude that botulinum toxin injections may provide safe and effective treatment in selected patients with writer's cramp.

摘要

书写痉挛是一种对大多数治疗方案都有抵抗性的局灶性肌张力障碍。本文描述了两名书写痉挛患者,他们通过在前臂肌肉注射肉毒杆菌毒素成功得到治疗。注射肌肉出现了因肉毒杆菌毒素作用导致的短暂无力。未观察到其他副作用。单次注射的有益效果持续三到四个月,并且在三年的随访期内通过重复注射可以再现。我们得出结论,肉毒杆菌毒素注射可能为选定的书写痉挛患者提供安全有效的治疗。

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