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上颌窦底提升术后 Schneiderian 膜对骨形成的影响:犬实验研究

Effect of the Schneiderian membrane on the formation of bone after lifting the floor of the maxillary sinus: an experimental study in dogs.

作者信息

Rong Q, Li X, Chen S L, Zhu S X, Huang D Y

机构信息

Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

出版信息

Br J Oral Maxillofac Surg. 2015 Sep;53(7):607-12. doi: 10.1016/j.bjoms.2015.02.010. Epub 2015 May 27.

Abstract

A titanium membrane was used to isolate the Schneiderian membrane of the bony walls of the sinus so that we could investigate their role on the formation of bone after sinus lifts compared with a control group (conventional raising of the sinus floor) in which we did not use a membrane to isolate any area. Three canine models of lifting the sinus floor using the lateral window technique were established: conventional lifting of the floor (control group), raising of the floor with the mucosa shielded (mucosal shielding group), and raising of the floor with the bony wall shielded (bony wall shielding group). The formation of bone one and three months after the sinus floor had been lifted was compared in each group both grossly and by histopathological examination. An appreciable amount of new bone had formed in the control group, with abundant areas near the inferior bony wall, and some near the raised Schneiderian membrane. Similarly, new bone had also formed in the mucosal shielding group, with abundant new bone near the inferior bony wall, but none near the raised Schneiderian membrane. However, there was considerably less new bone in the bony wall shielding group, with none in tissues adjacent to the inferior bony wall and little in tissues near the raised Schneiderian membrane. The Schneiderian membrane has osteogenic capability and participates in the formation of bone after the sinus floor has been lifted. However, its osteogenic role is weaker than that of the surrounding bony wall of the maxillary sinus.

摘要

使用钛膜隔离鼻窦骨壁的施奈德膜,以便与未使用膜隔离任何区域的对照组(传统的鼻窦底提升术)相比,我们能够研究其在鼻窦提升术后骨形成中的作用。建立了三个使用外侧开窗技术提升鼻窦底的犬模型:传统的鼻窦底提升术(对照组)、黏膜屏蔽提升鼻窦底(黏膜屏蔽组)和骨壁屏蔽提升鼻窦底(骨壁屏蔽组)。对每组鼻窦底提升术后1个月和3个月时的骨形成情况进行大体和组织病理学检查比较。对照组形成了相当数量的新骨,在下颌骨壁附近有大量区域,在抬高的施奈德膜附近也有一些。同样,黏膜屏蔽组也形成了新骨,在下颌骨壁附近有大量新骨,但在抬高的施奈德膜附近没有。然而,骨壁屏蔽组的新骨明显较少,在下颌骨壁相邻组织中没有新骨,在抬高的施奈德膜附近组织中也很少。施奈德膜具有成骨能力,在鼻窦底提升术后参与骨的形成。然而,其成骨作用比上颌窦周围的骨壁弱。

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