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使用可吸收胶原海绵进行上颌窦底提升术后的容积变化:一项回顾性队列研究。

Volumetric change after maxillary sinus floor elevation using absorbable collagen sponge: a retrospective cohort study.

作者信息

Han Yoon-Sic, Seo Byoung Moo

机构信息

Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul Metropolitan Government - Seoul National University Boramae Medical Center, Seoul, Korea.

Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2025 Apr 30;51(2):87-94. doi: 10.5125/jkaoms.2025.51.2.87.

DOI:10.5125/jkaoms.2025.51.2.87
PMID:40296732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12041428/
Abstract

OBJECTIVES

: To evaluate changes in bone volume induced by absorbable collagen sponge (ACS) use during maxillary sinus floor elevation and to identify associated factors.

PATIENTS AND METHODS

After elevating the sinus membrane through a crestal approach (CA) or lateral approach (LA), ACS (AteloPlug; Bioland) was inserted, and dental implants were placed simultaneously. Changes in bone volume at 12 months were evaluated by three-dimensional (3D) analyses of cone-beam computed tomography images. Factors including age, sex, smoking status, span, number of ACSs, and perforation were assessed for associations with changes in sinus bone volume using uni- and multivariable analyses based on the generalized estimating equation.

RESULTS

: Medical records of 108 patients were collected and retrospectively evaluated, with 135 regions of interest defined (CA, 45; LA, 90). The changes in bone volume at the sinus floor were 159.38±134.52 mm and 486.83±253.14 mm in the CA and LA groups, respectively. Bone volume changes in the CA group were significantly affected by the number of ACSs (<0.001) and perforation of the sinus membrane (<0.001), whereas bone volume changes in the LA group were significantly affected by the number of ACSs (=0.001).

CONCLUSION

: Use of ACS for maxillary sinus elevation resulted in detection of new bone formation in 3D analysis. Clinicians can ensure stable amounts of bone formation by inserting an adequate number of ACSs.

摘要

目的

评估在上颌窦底提升术中使用可吸收胶原海绵(ACS)引起的骨体积变化,并确定相关因素。

患者和方法

通过牙槽嵴顶入路(CA)或外侧入路(LA)提升窦膜后,插入ACS(AteloPlug;Bioland),并同时植入牙种植体。通过锥形束计算机断层扫描图像的三维(3D)分析评估12个月时的骨体积变化。使用基于广义估计方程的单变量和多变量分析评估年龄、性别、吸烟状况、跨度、ACS数量和穿孔等因素与窦骨体积变化的相关性。

结果

收集并回顾性评估了108例患者的病历,定义了135个感兴趣区域(CA组45个;LA组90个)。CA组和LA组窦底的骨体积变化分别为159.38±134.52mm和486.83±253.14mm。CA组的骨体积变化受ACS数量(<0.001)和窦膜穿孔(<0.001)的显著影响,而LA组的骨体积变化受ACS数量(=0.001)的显著影响。

结论

在3D分析中,使用ACS进行上颌窦提升可检测到新骨形成。临床医生可以通过插入足够数量的ACS来确保稳定的骨形成量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/616e25e25772/jkaoms-51-2-87-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/075c39f860e4/jkaoms-51-2-87-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/3211ece3192d/jkaoms-51-2-87-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/616e25e25772/jkaoms-51-2-87-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/075c39f860e4/jkaoms-51-2-87-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/3211ece3192d/jkaoms-51-2-87-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26c3/12041428/616e25e25772/jkaoms-51-2-87-f3.jpg

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本文引用的文献

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Dent J (Basel). 2022 Apr 2;10(4):58. doi: 10.3390/dj10040058.
2
Osteotome-Induced Blood Clot and Subsequent Bone Formation with the Use of Collagen Sponge for Integration of Single Dental Implants into the Atrophied Posterior Maxilla: A Retrospective Follow-Up of 36 Implants after 5 to 13 years.使用胶原海绵通过骨凿诱导血凝块及后续骨形成,将单颗牙种植体植入萎缩后上颌骨的研究:36颗种植体5至13年的回顾性随访
Int J Dent. 2022 Jan 5;2022:6594279. doi: 10.1155/2022/6594279. eCollection 2022.
3
Implant placement with sinus floor elevation via the lateral approach using only absorbable collagen sponge: 12-month post-loading radiographical outcomes and implant survival rate.
经外侧径路行鼻窦底提升并用可吸收胶原海绵行种植体植入:加载后 12 个月的放射学结果和种植体存活率。
Oral Maxillofac Surg. 2021 Jun;25(2):231-236. doi: 10.1007/s10006-020-00908-w. Epub 2020 Sep 22.
4
Sinus Floor Augmentation With Ambient Blood and an Absorbable Collagen Sponge: A Prospective Pilot Clinical Study.应用环境血和可吸收胶原海绵的鼻窦底提升术:一项前瞻性的初步临床研究。
Implant Dent. 2017 Oct;26(5):674-681. doi: 10.1097/ID.0000000000000631.
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Newly Formed Bone Induced by Recombinant Human Bone Morphogenetic Protein-2: A Histological Observation.重组人骨形态发生蛋白-2诱导的新形成骨:组织学观察
Implant Dent. 2017 Apr;26(2):173-177. doi: 10.1097/ID.0000000000000564.
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Sinus mucosa elevation using Bio-Oss or Gingistat collagen sponge: an experimental study in rabbits.使用 Bio-Oss 或 Gingistat 胶原海绵提升窦黏膜:兔的实验研究。
Clin Oral Implants Res. 2017 Jul;28(7):e21-e30. doi: 10.1111/clr.12850. Epub 2016 Apr 15.
7
Effect of the Schneiderian membrane on the formation of bone after lifting the floor of the maxillary sinus: an experimental study in dogs.上颌窦底提升术后 Schneiderian 膜对骨形成的影响:犬实验研究
Br J Oral Maxillofac Surg. 2015 Sep;53(7):607-12. doi: 10.1016/j.bjoms.2015.02.010. Epub 2015 May 27.
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Sinus augmentation using rhBMP-2/ACS in a mini-pig model: relative efficacy of autogenous fresh particulate iliac bone grafts.使用 rhBMP-2/ACS 在小型猪模型中进行鼻窦增大:自体新鲜颗粒髂骨移植物的相对疗效。
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