非结核分枝杆菌所致慢性化脓性中耳炎：一例局部应用硼酸成功治疗的病例
Chronic suppurative otitis media due to nontuberculous mycobacteria: A case of successful treatment with topical boric acid.
作者信息
Lefebvre Marie-Astrid, Quach Caroline, Daniel Sam J
机构信息
Infectious Diseases Division, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3.
Infectious Diseases Division, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3; Department of Medical Microbiology, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3; Department of Epidemiology, Biostatistics & Occupational Health, McGill University, Purvis Hall, 1020 Pine Avenue West, Montreal, Quebec, Canada H3A 1A2.
出版信息
Int J Pediatr Otorhinolaryngol. 2015 Jul;79(7):1158-60. doi: 10.1016/j.ijporl.2015.04.043. Epub 2015 May 8.
Nontuberculous mycobacteria (NTM) are an increasingly recognized cause of chronic suppurative otitis media in children with tympanostomy tubes. Treatment of this condition is difficult and typically requires a combination of systemic antibiotics and surgical debridement. We present the first case of a 2-year-old male with chronic suppurative otitis media due to NTM who failed systemic antibiotic therapy and was successfully managed with topical boric acid powder. This report highlights the challenges involved in treating this infection, and introduces boric acid as a potentially valuable component of therapy.
非结核分枝杆菌（NTM）是鼓膜造孔置管儿童慢性化脓性中耳炎日益被认识到的病因。这种病症的治疗困难，通常需要全身用抗生素和手术清创术联合使用。我们报告首例因NTM导致慢性化脓性中耳炎的2岁男性患儿，其全身用抗生素治疗失败，而局部应用硼酸粉成功治愈。本报告强调了治疗这种感染所涉及的挑战，并介绍硼酸作为一种可能有价值的治疗成分。
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