Roca I, Akova M, Baquero F, Carlet J, Cavaleri M, Coenen S, Cohen J, Findlay D, Gyssens I, Heuer O E, Kahlmeter G, Kruse H, Laxminarayan R, Liébana E, López-Cerero L, MacGowan A, Martins M, Rodríguez-Baño J, Rolain J-M, Segovia C, Sigauque B, Tacconelli E, Wellington E, Vila J
ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Department of Medicine, Section of Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey ; ESCMID Executive Committee, Basel, Switzerland.
New Microbes New Infect. 2015 Apr 16;6:22-9. doi: 10.1016/j.nmni.2015.02.007. eCollection 2015 Jul.
In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant bacteria are currently considered as an emergent global disease and a major public health problem. The B-Debate meeting brought together renowned experts representing the main stakeholders (i.e. policy makers, public health authorities, regulatory agencies, pharmaceutical companies and the scientific community at large) to review the global threat of antibiotic resistance and come up with a coordinated set of strategies to fight antimicrobial resistance in a multifaceted approach. We summarize the views of the B-Debate participants regarding the current situation of antimicrobial resistance in animals and the food chain, within the community and the healthcare setting as well as the role of the environment and the development of novel diagnostic and therapeutic strategies, providing expert recommendations to tackle the global threat of antimicrobial resistance.
在过去十年中,我们目睹了对多种抗菌药物耐药的细菌病原体比例和绝对数量的急剧增加。耐多药细菌目前被视为一种新出现的全球疾病和一个主要的公共卫生问题。B-Debate会议汇聚了代表主要利益相关者(即政策制定者、公共卫生当局、监管机构、制药公司和广大科学界)的知名专家,以审视抗生素耐药性的全球威胁,并提出一套协调一致的策略,以多方面的方法对抗抗菌药物耐药性。我们总结了B-Debate参与者对于动物和食物链、社区以及医疗环境中抗菌药物耐药性现状的看法,以及环境的作用和新型诊断与治疗策略的发展情况,提供了应对抗菌药物耐药性全球威胁的专家建议。