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低密度脂蛋白胆固醇目标值改变后医生的行为。

Physicians' behavior following changes in LDL cholesterol target goals.

作者信息

Vinker Shlomo, Bitterman Haim, Comaneshter Doron, Cohen Arnon D

机构信息

Chief Physician Office, Central Headquarter, Clalit Health Services, Tel Aviv, Israel ; Department of Family Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Chief Physician Office, Central Headquarter, Clalit Health Services, Tel Aviv, Israel.

出版信息

Isr J Health Policy Res. 2015 Jun 1;4:20. doi: 10.1186/s13584-015-0016-9. eCollection 2015.

Abstract

BACKGROUND

In 01/2011 Clalit Health Services (CHS), changed the LDL-Cholesterol target definitions in its quality indicators program, from a universal target to values stratified by risk assessment based on ATP III criteria. The objective of this study is to evaluate the effect of this change on achievement of LDL-C targets and on physicians' prescriptions of statins.

STUDY DESIGN

A descriptive study based on administrative dataset 06/2010-06/2012.

SETTING

CHS, The largest health maintenance organization in Israel that insures above 4,000,000 beneficiaries.

PATIENTS

PATIENTS who had been in the same risk group throughout the study period.

MEASUREMENTS

Attainment of targets for LDL-C and purchases of statins prior to, and following, implementation of the guidelines in the CHS quality indicators program.

RESULTS

433,662 patients remained in the same risk groups throughout the study period; 55.8% were women; the average age was 53.0 ± 10.3 years; 63.9%, 13.4%, and 22.7% were at low, medium, and high risk respectively. After implementation, the proportion of patients reaching LDL-C targets increased in all risk groups: from 58.6% to 61.6%, from 55.1% to 61.1%, and from 44.5% to 49.0%, in low, medium, and high risk groups respectively (p < 0.001). The proportion of patients treated with potent statins increased in all risk groups; from 3.4% to 5.6%, from 6.7% to 10.3%, and from 14.5% to 20.3% respectively (p < 0.001).

CONCLUSION

The risk stratification approach as a basis for the quality indicators program was implemented and better achievement of target LDL-C levels ensued. We suggest that implementation of quality indicators that are consistent with the current literature can lead to improvements that exceeds temporal trends.

摘要

背景

2011年1月,克拉利特医疗服务机构(CHS)在其质量指标项目中更改了低密度脂蛋白胆固醇(LDL - Cholesterol)目标定义,从通用目标改为基于ATP III标准通过风险评估分层的值。本研究的目的是评估这一变化对LDL - C目标达成情况以及医生他汀类药物处方的影响。

研究设计

基于2010年6月至2012年6月行政数据集的描述性研究。

研究背景

CHS,以色列最大的健康维护组织,为超过400万受益人提供保险。

研究对象

在整个研究期间处于同一风险组的患者。

测量指标

CHS质量指标项目中指南实施前后LDL - C目标的达成情况以及他汀类药物的购买情况。

结果

433,662名患者在整个研究期间处于同一风险组;55.8%为女性;平均年龄为53.0±10.3岁;分别有63.9%、13.4%和22.7%处于低、中、高风险。实施后,所有风险组中达到LDL - C目标的患者比例均有所增加:低风险组从58.6%增至61.6%,中风险组从55.1%增至61.1%,高风险组从44.5%增至49.0%(p<0.001)。所有风险组中接受强效他汀类药物治疗的患者比例均有所增加;分别从3.4%增至5.6%,从6.7%增至10.3%,从14.5%增至20.3%(p<0.001)。

结论

以风险分层方法为基础的质量指标项目得以实施,随后LDL - C目标水平的达成情况有所改善。我们建议,实施与当前文献一致的质量指标可带来超越时间趋势的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/031e/4450467/a0f56036e452/13584_2015_16_Fig1_HTML.jpg

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