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在一位对多种药物过敏的孕妇中进行头孢洛林脱敏程序。

Ceftaroline desensitization procedure in a pregnant patient with multiple drug allergies.

机构信息

Division of Rheumatology, Allergy, and Immunology, Department of Medicine , Massachusetts General Hospital ; Harvard Medical School.

Division of Rheumatology, Allergy, and Immunology, Department of Medicine , Massachusetts General Hospital ; Harvard Medical School ; Medical Practice Evaluation Center , Massachusetts General Hospital.

出版信息

Open Forum Infect Dis. 2015 Mar 23;2(1):ofv027. doi: 10.1093/ofid/ofv027. eCollection 2015 Jan.

DOI:10.1093/ofid/ofv027
PMID:26034776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4438906/
Abstract

Validated skin testing is lacking for many drugs, including ceftaroline. The cross-reactivity between ceftaroline and other β-lactam antibiotics is unknown. We report a case of a pregnant patient with cystic fibrosis and multiple drug allergies who required ceftaroline for methicillin-resistant Staphylococcus aureus pneumonia and underwent an uncomplicated empiric desensitization procedure.

摘要

许多药物(包括头孢洛林)的皮肤测试尚未得到验证。头孢洛林与其他β-内酰胺类抗生素之间的交叉反应性尚不清楚。我们报告了 1 例患有囊性纤维化和多种药物过敏的孕妇,因耐甲氧西林金黄色葡萄球菌肺炎需要使用头孢洛林,并进行了简单的经验性脱敏程序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93e4/4438906/74fc319d4d6c/ofv02701.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93e4/4438906/74fc319d4d6c/ofv02701.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93e4/4438906/74fc319d4d6c/ofv02701.jpg

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本文引用的文献

1
Desensitization to ceftaroline in a patient with multiple medication hypersensitivity reactions.一名患有多种药物过敏反应患者对头孢洛林的脱敏治疗
Am J Health Syst Pharm. 2015 Feb 1;72(3):198-202. doi: 10.2146/ajhp140151.
2
Ceftaroline: clinical and microbiology experience with focus on methicillin-resistant Staphylococcus aureus after regulatory approval in the USA.头孢洛林:在美国获批后针对耐甲氧西林金黄色葡萄球菌的临床及微生物学经验
Diagn Microbiol Infect Dis. 2015 Mar;81(3):183-8. doi: 10.1016/j.diagmicrobio.2014.11.016. Epub 2014 Dec 3.
3
Safety and outcomes of test doses for the evaluation of adverse drug reactions: a 5-year retrospective review.
药物不良反应评估中测试剂量的安全性和结果:一项 5 年回顾性研究。
J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):768-74. doi: 10.1016/j.jaip.2014.08.001. Epub 2014 Sep 10.
4
Evaluation and management of a patient with multiple drug allergies.多药过敏患者的评估与管理。
Allergy Asthma Proc. 2014 May-Jun;35(3):197-203. doi: 10.2500/aap.2014.35.3739.
5
Penicillin and cephalosporin allergy.青霉素和头孢菌素过敏。
Ann Allergy Asthma Immunol. 2014 May;112(5):404-12. doi: 10.1016/j.anai.2014.02.005.
6
Methicillin-resistant Staphylococcus aureus nosocomial pneumonia patients treated with ceftaroline: retrospective case series of 10 patients.用头孢洛林治疗耐甲氧西林金黄色葡萄球菌医院获得性肺炎患者:10例患者的回顾性病例系列研究
J Chemother. 2015 Feb;27(1):29-34. doi: 10.1179/1973947813Y.0000000156. Epub 2013 Dec 19.
7
Large retrospective evaluation of the effectiveness and safety of ceftaroline fosamil therapy.头孢洛林酯治疗有效性和安全性的大型回顾性评估
Antimicrob Agents Chemother. 2014 May;58(5):2541-6. doi: 10.1128/AAC.02371-13. Epub 2014 Feb 18.
8
Summary of ceftaroline fosamil clinical trial studies and clinical safety.头孢洛林酯临床试验研究及临床安全性概述。
Clin Infect Dis. 2012 Sep;55 Suppl 3:S173-80. doi: 10.1093/cid/cis559.
9
Epidemiology and risk factors for drug allergy.药物过敏的流行病学和危险因素。
Br J Clin Pharmacol. 2011 May;71(5):684-700. doi: 10.1111/j.1365-2125.2010.03774.x.
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ACOG Committee Opinion No. 485: Prevention of early-onset group B streptococcal disease in newborns.美国妇产科医师学会委员会意见 No.485:预防新生儿早发型 B 群链球菌病。
Obstet Gynecol. 2011 Apr;117(4):1019-1027. doi: 10.1097/AOG.0b013e318219229b.