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孕期卵巢癌患者的奥沙利铂脱敏治疗：一例报告

Oxaliplatin desensitization for ovarian in pregnancy: A case report.

作者信息

Nicholson Kaitlin, Jia Lily, Rowe Margaret, Esselen Katharine, Joseph Naima, Zera Chloe A, Lax Timothy, Shea Meghan

机构信息

Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, United States.

Harvard Medical School, Boston, MA, United States.

出版信息

Gynecol Oncol Rep. 2024 Feb 28;52:101354. doi: 10.1016/j.gore.2024.101354. eCollection 2024 Apr.

DOI:10.1016/j.gore.2024.101354
PMID:38435348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10909594/
Abstract

•Incidence of cancer in pregnancy is rising and successful treatment of these patients requires expert multidisciplinary care.•Platinum hypersensitivity reactions in ovarian cancer are commonly treated with desensitization protocols.•To our knowledge, chemotherapy desensitization in pregnant patients has not been previously reported.•Oxaliplatin desensitization during pregnancy may be safe and feasible.

摘要

•妊娠期间癌症的发病率在上升，对这些患者进行成功治疗需要专家多学科护理。

•卵巢癌中的铂类超敏反应通常采用脱敏方案治疗。

•据我们所知，此前尚未报道过对孕妇进行化疗脱敏。

•孕期奥沙利铂脱敏可能是安全可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e034/10909594/c14d0544b915/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e034/10909594/a2b859fe728b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e034/10909594/c14d0544b915/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e034/10909594/a2b859fe728b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e034/10909594/c14d0544b915/gr2.jpg

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本文引用的文献

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Rechallenge After Oxaliplatin-Induced Hypersensitivity Reactions.奥沙利铂诱导的超敏反应后的再激发
JAMA Oncol. 2023 Mar 1;9(3):434-435. doi: 10.1001/jamaoncol.2022.7136.
2
Drug desensitization during pregnancy: Improving patient safety through multidisciplinary collaborative approach.孕期药物脱敏：通过多学科协作方法提高患者安全性。
J Allergy Clin Immunol Pract. 2023 Feb;11(2):647-649.e2. doi: 10.1016/j.jaip.2022.11.014. Epub 2022 Dec 2.
3
Rapid drug desensitization with platin-based chemotherapy: Analysis of risk factors for breakthrough reactions.
基于铂类化疗的快速药物脱敏：突破性反应的危险因素分析。
World Allergy Organ J. 2021 Dec 20;15(1):100619. doi: 10.1016/j.waojou.2021.100619. eCollection 2022 Jan.
4
Hypersensitivity reactions to chemotherapy: an EAACI Position Paper.化疗药物过敏反应：欧洲过敏与临床免疫学会立场文件
Allergy. 2022 Feb;77(2):388-403. doi: 10.1111/all.15113. Epub 2021 Oct 26.
5
Anaphylaxis and Pregnancy: A Systematic Review and Call for Public Health Actions.过敏反应与妊娠：系统评价及公共卫生行动呼吁
J Allergy Clin Immunol Pract. 2021 Dec;9(12):4270-4278. doi: 10.1016/j.jaip.2021.07.046. Epub 2021 Aug 5.
6
Algorithm to guide re-exposure to penicillin in allergic pregnant women with syphilis: Efficacy and safety.指导梅毒过敏孕妇再次接触青霉素的算法：疗效与安全性
World Allergy Organ J. 2021 May 21;14(6):100549. doi: 10.1016/j.waojou.2021.100549. eCollection 2021 Jun.
7
Gynecologic cancers in pregnancy: guidelines based on a third international consensus meeting.妊娠妇科癌症：基于第三次国际共识会议的指南。
Ann Oncol. 2019 Oct 1;30(10):1601-1612. doi: 10.1093/annonc/mdz228.
8
Ceftaroline desensitization procedure in a pregnant patient with multiple drug allergies.在一位对多种药物过敏的孕妇中进行头孢洛林脱敏程序。
Open Forum Infect Dis. 2015 Mar 23;2(1):ofv027. doi: 10.1093/ofid/ofv027. eCollection 2015 Jan.
9
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J Natl Compr Canc Netw. 2014 Mar 1;12(3):389-402. doi: 10.6004/jnccn.2014.0040.
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