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采用纽扣电极的等离子体动力学前列腺汽化剜除术与前列腺等离子体动力学切除术治疗体积>90ml的良性前列腺增生:一项前瞻性随机临床试验的围手术期及3个月随访结果

Plasmakinetic Vapor Enucleation of the Prostate with Button Electrode versus Plasmakinetic Resection of the Prostate for Benign Prostatic Enlargement >90 ml: Perioperative and 3-Month Follow-Up Results of a Prospective, Randomized Clinical Trial.

作者信息

Zhang Keqin, Sun Dingqi, Zhang Hui, Cao Qingwei, Fu Qiang

机构信息

Department of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, PR China.

出版信息

Urol Int. 2015;95(3):260-4. doi: 10.1159/000381753. Epub 2015 Jun 2.

DOI:10.1159/000381753
PMID:26044933
Abstract

OBJECTIVE

To evaluate plasmakinetic vapor enucleation of the prostate (PVEP) with button electrode and plasmakinetic resection of the prostate (PKRP) in patients with urinary symptoms due to benign prostatic enlargement (BPE) >90 ml.

METHODS

A total of 112 patients with symptomatic BPE were randomly assigned to either PKRP or PVEP prospectively from August 2012 to May 2014 in our department. Perioperative and postoperative data were investigated during a 3-month follow-up.

RESULTS

PVEP was significantly superior to PKRP in terms of operation time (63.9 ± 7.7 vs. 78.1 ± 13.6 min, p < 0.001), hemoglobin loss (1.18 ± 0.30 vs. 1.63 ± 0.38 g/dl, p < 0.001), serum sodium decrease (2.9 ± 0.7 vs. 4.3 ± 0.8 mmol/l, p < 0.001), catheterization duration (49.3 ± 12.2 vs. 78.1 ± 14.8 h, p < 0.001) and hospital stay (100.2 ± 28.3 vs. 116.0 ± 29.2 h, p = 0.004). There were no statistical differences in blood transfusion between the two groups. In addition, there were no statistical differences in maximum urinary flow rate, International Prostate Symptom Score, postvoid residual urine volume, quality-of-life score, transient incontinence, and urethral stricture at 3 months postoperatively.

CONCLUSIONS

PVEP with button electrode is an equally effective technique for treatment of large BPE with PKRP, with more safety and faster recovery. It may become the superior alternative to PKRP for patients with large BPE.

摘要

目的

评估纽扣电极等离子体动力学汽化前列腺切除术(PVEP)与等离子体动力学前列腺切除术(PKRP)治疗良性前列腺增生(BPE)体积>90ml且有排尿症状患者的效果。

方法

2012年8月至2014年5月,我科将112例有症状的BPE患者前瞻性地随机分为PKRP组或PVEP组。在3个月的随访期间调查围手术期和术后数据。

结果

在手术时间(63.9±7.7 vs. 78.1±13.6分钟,p<0.001)、血红蛋白丢失(1.18±0.30 vs. 1.63±0.38g/dl,p<0.001)、血清钠降低(2.9±0.7 vs. 4.3±0.8mmol/l,p<0.001)、导尿持续时间(49.3±12.2 vs. 78.1±14.8小时,p<0.001)和住院时间(100.2±28.3 vs. 116.0±29.2小时,p = 0.004)方面,PVEP显著优于PKRP。两组间输血情况无统计学差异。此外,术后3个月时,两组在最大尿流率、国际前列腺症状评分、残余尿量、生活质量评分、短暂性尿失禁和尿道狭窄方面无统计学差异。

结论

纽扣电极PVEP是一种与PKRP治疗大体积BPE同样有效的技术,安全性更高且恢复更快。对于大体积BPE患者,它可能成为PKRP的更佳替代方法。

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