Blondin G, Bingen E, Lambert N, Mercier J C, Aujard Y
Clinique de Pédiatrie, Hôpital Robert-Debré, Paris.
Arch Fr Pediatr. 1989 Nov;46(9):641-4.
Toxic shock syndrome (TSS) is reported in 2 children. TSS occurred 10 days after an accidental injury of the fore foot in one case and 5 days following surgery for severe uretero-vesical reflux in the other. The clinical illness was defined by the case definition formulated for epidemiologic studies (CDC, 1982). The diagnosis was confirmed by isolation of a Staphylococcus aureus strain producing TSST, at the infected site. Toxin-induced mediators such as interleukin I and Tumor Necrosis Factor have been incriminated in septic shock with multivisceral involvement. As in our 2 cases, the syndrome may be delayed or even absent.
有2名儿童被报告患有中毒性休克综合征（TSS）。其中1例在足前部意外受伤10天后发生TSS，另一例在严重输尿管膀胱反流手术后5天发生。临床疾病根据为流行病学研究制定的病例定义（疾病控制与预防中心，1982年）确定。通过在感染部位分离出产生中毒性休克综合征毒素（TSST）的金黄色葡萄球菌菌株确诊。毒素诱导的介质如白细胞介素I和肿瘤坏死因子被认为与多脏器受累的感染性休克有关。正如我们这2例病例所示，该综合征可能会延迟出现甚至不出现。
