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Skin test evaluation of a novel peptide carrier-based vaccine, BM32, in grass pollen-allergic patients.

作者信息

Niederberger Verena, Marth Katharina, Eckl-Dorna Julia, Focke-Tejkl Margarete, Weber Milena, Hemmer Wolfgang, Berger Uwe, Neubauer Angela, Stolz Frank, Henning Rainer, Valenta Rudolf

机构信息

Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.

Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria; Division of Immunopathology, Department of Pathophysiology and Allergy Research, Centre for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

出版信息

J Allergy Clin Immunol. 2015 Oct;136(4):1101-3.e8. doi: 10.1016/j.jaci.2015.03.034. Epub 2015 Jun 3.

DOI:10.1016/j.jaci.2015.03.034
PMID:26048664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6536382/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/edd1b3511d78/EMS83027-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/7a056ca71059/EMS83027-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/5b6a0004a802/EMS83027-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/e8172b663405/EMS83027-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/291275b5ec5b/EMS83027-f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/edd1b3511d78/EMS83027-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/7a056ca71059/EMS83027-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/5b6a0004a802/EMS83027-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/e8172b663405/EMS83027-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/291275b5ec5b/EMS83027-f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a147/6536382/edd1b3511d78/EMS83027-f001.jpg

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本文引用的文献

1
Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.一种用于草花粉过敏的重组、低变应原性、基于肽的疫苗的研发与特性分析。
J Allergy Clin Immunol. 2015 May;135(5):1207-7.e1-11. doi: 10.1016/j.jaci.2014.09.012. Epub 2014 Nov 13.
2
Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides.基于连续重叠肽的新型桦树花粉特异性免疫治疗制剂。
Clin Transl Allergy. 2013 Jun 1;3(1):17. doi: 10.1186/2045-7022-3-17.
3
Allergen-specific immunotherapy: from therapeutic vaccines to prophylactic approaches.过敏原特异性免疫治疗：从治疗性疫苗到预防性方法。
J Intern Med. 2012 Aug;272(2):144-57. doi: 10.1111/j.1365-2796.2012.02556.x.
4
Heterogeneity of commercial timothy grass pollen extracts.市售梯牧草花粉提取物的异质性。
Clin Exp Allergy. 2008 Aug;38(8):1400-8. doi: 10.1111/j.1365-2222.2008.03031.x. Epub 2008 Jun 28.
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Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.在人体中分析由结构折叠和未折叠的重组Bet v 1变应原衍生物疫苗接种诱导的表位特异性免疫反应。
J Immunol. 2007 Oct 15;179(8):5309-16. doi: 10.4049/jimmunol.179.8.5309.
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Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study.特异性免疫疗法对季节性和常年性哮喘具有长期预防作用：PAT研究的10年随访
Allergy. 2007 Aug;62(8):943-8. doi: 10.1111/j.1398-9995.2007.01451.x.
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EAACI/GA2LEN position paper: present status of the atopy patch test.欧洲变态反应和临床免疫学会/全球过敏和哮喘欧洲网络立场文件：特应性斑贴试验的现状
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Proc Natl Acad Sci U S A. 2004 Oct 5;101 Suppl 2(Suppl 2):14677-82. doi: 10.1073/pnas.0404735101. Epub 2004 Aug 13.
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Allergen-specific immunotherapy in birch- and grass-pollen-allergic rhinitis. II. Side-effects.桦树花粉和草花粉过敏性鼻炎的变应原特异性免疫疗法。II. 副作用。
Allergy. 2000 Sep;55(9):827-35. doi: 10.1034/j.1398-9995.2000.00368.x.