Jacob Sabrina Anne, Ab Rahman Ab Fatah, Hassali Mohamed Azmi Ahmad
School of Pharmacy, Monash University Malaysia, Sunway, Malaysia.
Faculty of Health Sciences, Gong Badak Campus, Universiti Sultan Zainal Abidin (UniSZA), Kuala Terengganu, Malaysia.
Neuropsychiatr Dis Treat. 2015 May 27;11:1339-47. doi: 10.2147/NDT.S82563. eCollection 2015.
Many patients have erroneous views with regard to depression and its management, and it was noted that these attitudes and beliefs significantly affected their adherence rates.
The primary aim of this study was to determine the attitudes and beliefs of patients with depression toward depression and antidepressants. A secondary aim was to assess the influence of ethnicity on patients' attitudes and beliefs.
The study involved patients with chronic depression being followed up at an outpatient clinic at a government-run hospital in Malaysia. Patients' attitudes and beliefs were assessed using the Antidepressant Compliance Questionnaire.
A total of 104 patients of Malay, Chinese, and Indian ethnic groups met the selection criteria. Chinese patients had significantly negative attitudes and beliefs toward depression and antidepressants compared to Malays and Indians (b=-8.96, t 103=-3.22; P<0.05). Component analysis revealed that 59% of patients believed that antidepressants can cause a person to have less control over their thoughts and feelings, while 67% believed that antidepressants could alter one's personality; 60% believed it was okay to take fewer tablets on days when they felt better, while 66% believed that antidepressants helped solve their emotional problems and helped them worry less.
Patients had an overall positive view as to the benefits of antidepressants, but the majority had incorrect views as to the acceptable dosing of antidepressants and had concerns about the safety of the medication. Assessing patients' attitudes and beliefs, as well as the impact of their respective cultures, can be used in tailoring psychoeducation sessions accordingly.
许多患者对抑郁症及其治疗存在错误观念，并且注意到这些态度和信念显著影响了他们的依从率。
本研究的主要目的是确定抑郁症患者对抑郁症和抗抑郁药的态度和信念。次要目的是评估种族对患者态度和信念的影响。
该研究纳入了在马来西亚一家政府医院门诊接受随访的慢性抑郁症患者。使用抗抑郁药依从性问卷评估患者的态度和信念。
共有104名马来族、华裔和印度族患者符合入选标准。与马来族和印度族患者相比，华裔患者对抑郁症和抗抑郁药持有明显负面的态度和信念（b=-8.96，t 103=-3.22；P<0.05）。成分分析显示，59%的患者认为抗抑郁药会使人对自己的思想和情感控制能力下降，而67%的患者认为抗抑郁药会改变一个人的性格；60%的患者认为在感觉较好的日子里少服药是可以的，而66%的患者认为抗抑郁药有助于解决他们的情绪问题并减少担忧。
患者总体上对抗抑郁药的益处持积极看法，但大多数患者对抗抑郁药的可接受剂量存在错误观念，并对药物安全性有所担忧。评估患者的态度和信念以及各自文化的影响，可用于相应地定制心理教育课程。
