Elterman Dean S
Division of Urology, Department of Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Can J Urol. 2015 Jun;22(3):7836-43.
The treatments for benign prostate enlargement (BPE), also known as lower urinary tract symptoms secondary to benign prostatic hypertrophy (BPH-LUTS), have evolved significantly over recent years. Where transurethral resection of the prostate (TURP) has been the gold standard surgery for enlarged prostate glands < 80 grams, newer modalities such as laser technology have proliferated with safe and efficacious results. Notably, for prostates larger than 80-100 grams, the surgical options were an open, simple prostatectomy or perhaps a staged TURP. Both of these surgeries have the potential for bleeding complications, electrolyte abnormalities, and prolonged hospital admissions. Additional demographic and healthcare forces are also at play. Our aging population of men is being increasingly successfully treated for cardiovascular disease. This means more men are on anti-coagulation therapy, many of whom must stay on these drugs to prevent stent clotting or stroke. Hospital resources, especially overnight hospital admissions do add considerable strain to our healthcare systems. Men are also increasingly becoming more savvy consumers when it comes to their health. Many male patients would prefer to take as few medications as possible. Studies of BPH medications in Europe and the United States have shown drug discontinuation rates between 58%-70% at 1 year. Men who are faced with the choice of daily medication for life versus an outpatient procedure will often opt for the latter, which is in keeping with AUA guidelines that still put surgery as a patient choice alongside medications. Being able to offer GreenLight photoselective vaporization (GL-PVP) with the GreenLight XPS 180Watt system addresses all of these concerns. Men with bothersome BPH-LUTS with essentially any sized prostate gland, can be treated as same-day surgery requiring no overnight admission to hospital, while continuing necessary anti-coagulants, with significantly diminished risks of bleeding, erectile dysfunction, TUR-syndrome. Just as there are many ways to perform a TURP, techniques for GL-PVP do vary. The objectives of this article are to breakdown some of the basic steps for the novice user of GL-PVP, as well as impart some 'pearls' for the more experienced user. Nothing can replace hands-on experience for any surgery. The GL-PVP is unique in that there are guides such as this and previous articles, an excellent simulation device (GreenLight SIM), and mentoring programs in place. The success of many surgeries has been the standardization of the procedure. Performing GL-PVP should not be haphazard. A surgical plan based on prostate anatomy and size, cystoscopic appearance, and application of routinized techniques should yield consistent and optimal surgical outcomes.
良性前列腺增生(BPE)的治疗,也被称为继发于良性前列腺肥大的下尿路症状(BPH-LUTS),近年来有了显著进展。对于重量小于80克的前列腺增生,经尿道前列腺切除术(TURP)一直是标准的手术方式,但诸如激光技术等更新的治疗方法已大量涌现,且效果安全有效。值得注意的是,对于重量超过80 - 100克的前列腺,手术选择是开放性简单前列腺切除术或分期TURP。这两种手术都有出血并发症、电解质异常和住院时间延长的风险。其他人口统计学和医疗因素也在起作用。我们不断老龄化的男性人口越来越成功地接受心血管疾病治疗。这意味着更多男性正在接受抗凝治疗,其中许多人必须持续服用这些药物以预防支架凝血或中风。医院资源,尤其是过夜住院,确实给我们的医疗系统增加了相当大的压力。男性在健康问题上也越来越精明。许多男性患者希望尽可能少用药。欧洲和美国对BPH药物的研究表明,1年后药物停药率在58% - 70%之间。面临终身每日服药与门诊手术选择的男性通常会选择后者,这与美国泌尿外科学会(AUA)的指南一致,该指南仍将手术作为患者与药物并列的选择。能够使用GreenLight XPS 180瓦系统进行绿激光选择性汽化术(GL-PVP)解决了所有这些问题。患有严重BPH-LUTS且前列腺大小基本任意的男性,可以作为日间手术进行治疗,无需过夜住院,同时继续必要的抗凝治疗,出血、勃起功能障碍、TUR综合征的风险显著降低。正如有多种实施TURP的方法一样,GL-PVP的技术也各不相同。本文的目的是为GL-PVP的新手用户分解一些基本步骤,并为经验更丰富的用户传授一些“诀窍”。对于任何手术来说,实践经验都是无可替代的。GL-PVP的独特之处在于有像本文及之前文章这样的指南、出色的模拟设备(GreenLight SIM)以及指导项目。许多手术的成功在于手术过程标准化。实施GL-PVP不应随意进行。基于前列腺解剖结构和大小、膀胱镜检查外观以及常规技术应用的手术计划应能产生一致且最佳的手术效果。