变色菌素C，一种从冲绳海洋海绵变色扁海绵中提取的新型细胞毒性倍半萜。
Metachromin C, a new cytotoxic sesquiterpenoid from the Okinawan marine sponge Hippospongia metachromia.
作者信息
Kobayashi J, Murayama T, Ohizumi Y, Ohta T, Nozoe S, Sasaki T
机构信息
Mitsubishi Kasie Institute of Life Sciences, Minamiooya, Machida, Tokyo, Japan.
出版信息
J Nat Prod. 1989 Sep-Oct;52(5):1173-7. doi: 10.1021/np50065a047.
PMID:2607352
Abstract
A new sesquiterpenoid quinone, metachromin C[1], with potent cytotoxic activity has been isolated together with a known terpenoid metachromin A[2] from the Okinawan marine sponge Hippospongia metachromia and the structure determined by spectroscopic data, especially several types of 2D nmr spectra including 1H-detected heteronuclear multiple-bone correlation (HMBC).
摘要
一种具有强细胞毒性活性的新倍半萜醌类化合物变色菌素C[1]，已与一种已知的萜类化合物变色菌素A[2]一起，从冲绳海洋海绵变色 Hippospongia metachromia中分离出来，并通过光谱数据，特别是包括1H检测的异核多键相关（HMBC）在内的几种二维核磁共振光谱确定了其结构。
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