预防性卵巢切除术用于治疗遗传性高钙血症型卵巢小细胞癌。
Prophylactic oophorectomy for hereditary small cell carcinoma of the ovary, hypercalcemic type.
作者信息
Berchuck Andrew, Witkowski Leora, Hasselblatt Martin, Foulkes William D
机构信息
Duke University Medical Center, Durham, NC, United States.
Department of Human Genetics, McGill University, Montreal, QC, Canada.
出版信息
Gynecol Oncol Rep. 2015 Feb 25;12:20-2. doi: 10.1016/j.gore.2015.02.002. eCollection 2015 Apr.
Abstract
•Prophylactic oophorectomy can prevent small cell carcinoma of the ovary, hypercalcemic type in carriers of germline SMARCA4 mutations.•Unaffected SMARCA4 mutation carriers who desire children may be best served by oocyte cryopreservation prior to prophylactic oophorectomy.
摘要
•预防性卵巢切除术可预防种系SMARCA4突变携带者发生高钙血症型卵巢小细胞癌。
•希望生育的未受影响的SMARCA4突变携带者，在进行预防性卵巢切除术之前，最好先进行卵母细胞冷冻保存。
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